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Y-SPCR: A new dimensionality reduction method for gene expression data classification

  • School of Computer Science and Technology, Harbin Institute of Technology

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

With the increase of the scale and complexity of massive data, data dimensionality reduction technologies, such as principal component analysis, have developed rapidly. The performance of dimension reduction technologies still needs to be further improved. In the paper we proposed a new dimensionality reduction method (Y-SPCR) based Supervised Principal Component Regression (SPCR) and Y-aware Principal Component Regression (Y-aware PCR). Experimental results on four gene expression data sets show that Y-SPCR effectively overcomes the shortcomings of SPCR and Y-aware PCR and improves the accuracy and stability of on gene expression data classification.

Original languageEnglish
Title of host publicationProceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019
EditorsIllhoi Yoo, Jinbo Bi, Xiaohua Tony Hu
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages401-408
Number of pages8
ISBN (Electronic)9781728118673
DOIs
StatePublished - Nov 2019
Externally publishedYes
Event2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019 - San Diego, United States
Duration: 18 Nov 201921 Nov 2019

Publication series

NameProceedings - 2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019

Conference

Conference2019 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2019
Country/TerritoryUnited States
CitySan Diego
Period18/11/1921/11/19

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • SPCR
  • Y-SPCR
  • Y-aware PCR
  • classification
  • data dimension reduction
  • gene expression data

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