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Ultrasensitive spectroscopy based on photonic waveguides on Al2O3/SiO2 platform

  • Elham Heidari
  • , Xiaochuan Xu
  • , Naimei Tang
  • , Farzad Mokhtari-Koushyar
  • , Hamed Dalir
  • , Ray T. Chen
  • University of Texas at Austin
  • Omega Optics Inc.

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Here a photonic waveguide on Al2O3/SiO2 platform is proposed to cover the 240∼320 nm wavelength-range, which is of paramount significance in protein and nuclei acid quantification. Our optical waveguide increases path-length and overlap integration for light-matter interaction with proteins. The proposed system detects one order less proteins concentration as low as 12.5 μg/ml compared with NanoDropTM that detects <125 μg/ml. Also, a linear absorbance change up to protein concentration of 7500 μg/ml is experimentally attained which is based on the Beer-Lambert-law.

Original languageEnglish
Title of host publicationOptical Diagnostics and Sensing XVIII
Subtitle of host publicationToward Point-of-Care Diagnostics
EditorsGerard L. Cote
PublisherSPIE
ISBN (Electronic)9781510614871
DOIs
StatePublished - 2018
Externally publishedYes
EventOptical Diagnostics and Sensing XVIII: Toward Point-of-Care Diagnostics 2018 - San Francisco, United States
Duration: 29 Jan 201830 Jan 2018

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10501
ISSN (Print)1605-7422

Conference

ConferenceOptical Diagnostics and Sensing XVIII: Toward Point-of-Care Diagnostics 2018
Country/TerritoryUnited States
CitySan Francisco
Period29/01/1830/01/18

Keywords

  • Optical Waveguide
  • Spectroscopy

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