Transition of cationic dipeptide nanotubes into vesicles and oligonucleotide delivery

Xuehai Yan; Qiang He; Kewei Wang; Li Duan; Yue Cui; Junbai Li

doi:10.1002/anie.200603387

Transition of cationic dipeptide nanotubes into vesicles and oligonucleotide delivery

Xuehai Yan^*
, Qiang He
, Kewei Wang
, Li Duan
, Yue Cui
, Junbai Li

^*Corresponding author for this work

CAS - Institute of Chemistry
Max Planck Institute of Colloids and Interfaces

Research output: Contribution to journal › Article › peer-review

341 Scopus citations

Abstract

(Figure Presented) Password? - Vesicle! A cationic dipeptide can self-assemble into nanotubes at physiological pH values. Such self-assembled cationic dipeptide nanotubes (CDPNTs) are able to convert into vesicles spontaneously upon dispersion dilution and thus carry single-stranded DNA into HeLa cells across the biomembrane (see picture).

Original language	English
Pages (from-to)	2431-2434
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	14
DOIs	https://doi.org/10.1002/anie.200603387
State	Published - 2007
Externally published	Yes

Keywords

Cells
Oligonucleotides
Peptide nanotubes
Self-assembly
Vesicles

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10.1002/anie.200603387

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title = "Transition of cationic dipeptide nanotubes into vesicles and oligonucleotide delivery",

abstract = "(Figure Presented) Password? - Vesicle! A cationic dipeptide can self-assemble into nanotubes at physiological pH values. Such self-assembled cationic dipeptide nanotubes (CDPNTs) are able to convert into vesicles spontaneously upon dispersion dilution and thus carry single-stranded DNA into HeLa cells across the biomembrane (see picture).",

keywords = "Cells, Oligonucleotides, Peptide nanotubes, Self-assembly, Vesicles",

author = "Xuehai Yan and Qiang He and Kewei Wang and Li Duan and Yue Cui and Junbai Li",

year = "2007",

doi = "10.1002/anie.200603387",

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volume = "46",

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T1 - Transition of cationic dipeptide nanotubes into vesicles and oligonucleotide delivery

AU - Yan, Xuehai

AU - He, Qiang

AU - Wang, Kewei

AU - Duan, Li

AU - Cui, Yue

AU - Li, Junbai

PY - 2007

Y1 - 2007

N2 - (Figure Presented) Password? - Vesicle! A cationic dipeptide can self-assemble into nanotubes at physiological pH values. Such self-assembled cationic dipeptide nanotubes (CDPNTs) are able to convert into vesicles spontaneously upon dispersion dilution and thus carry single-stranded DNA into HeLa cells across the biomembrane (see picture).

AB - (Figure Presented) Password? - Vesicle! A cationic dipeptide can self-assemble into nanotubes at physiological pH values. Such self-assembled cationic dipeptide nanotubes (CDPNTs) are able to convert into vesicles spontaneously upon dispersion dilution and thus carry single-stranded DNA into HeLa cells across the biomembrane (see picture).

KW - Cells

KW - Oligonucleotides

KW - Peptide nanotubes

KW - Self-assembly

KW - Vesicles

UR - https://www.scopus.com/pages/publications/34250841766

U2 - 10.1002/anie.200603387

DO - 10.1002/anie.200603387

M3 - 文章

AN - SCOPUS:34250841766

SN - 1433-7851

VL - 46

SP - 2431

EP - 2434

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 14

ER -

Transition of cationic dipeptide nanotubes into vesicles and oligonucleotide delivery

Abstract

Keywords

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