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Synthesis of natural product inulavosin via Ga(OTf)3-Catalyzed Hetero Diels–Alder Dimerization of salicyl alcohol derivative

  • School of Marine Science and Technology, Harbin Institute of Technology Weihai
  • Harbin Institute of Technology
  • Peking University

Research output: Contribution to journalArticlepeer-review

Abstract

Inulavosin, a natural melanogenesis inhibitor, has been synthesized smoothly from readily available and inexpensive starting materials by using a Ga(OTf)3-catalyzed room temperature hetero Diels–Alder dimerization of salicyl alcohol derivative and a regioselective phenol monobromination as the key steps.

Original languageEnglish
Pages (from-to)2911-2916
Number of pages6
JournalNatural Product Research
Volume33
Issue number20
DOIs
StatePublished - 2019
Externally publishedYes

Keywords

  • Diels–Alder reaction
  • Ga(OTf)3
  • Natural product
  • inulavosin
  • synthesis

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