Synthesis and characterization of poly(L-lactide-co-ε-caprolactone) copolymers

Xili Lu; Ye Wu; Wei Cai; Wenjun Tang

Synthesis and characterization of poly(L-lactide-co-ε-caprolactone) copolymers

Xili Lu^*
, Ye Wu
, Wei Cai
, Wenjun Tang

^*Corresponding author for this work

Harbin Institute of Technology

Research output: Contribution to journal › Article › peer-review

Abstract

A series of random and block poly(L-lactide-co-ε-caprolactone) (PCLA) copolymers with different composition are prepared using stannous octaoate as catalyst. The effects of the amount of initiator on the intrinsic viscosity have been investigated. The structure of the PCLA copolymers is characterized by means of nuclear magnetic resonance (NMR), Fourier transform, infrared spectrum (FTIR), differential scanning calorimetry (DSC) and X-ray diffraction (XRD) methods. It is shown that the synthesis condition and the composition of copolymers have obvious influence on the structure of PCLA copolymers. Hydrolytic degradation of the copolymers in a PBS solution of pH 7.4 at 37.0°C shows that the copolymers of different compositions degrade at different rates.

Original language	English
Pages (from-to)	287-289
Number of pages	3
Journal	Journal Wuhan University of Technology, Materials Science Edition
Volume	20
Issue number	SUPPL.
State	Published - Dec 2005
Externally published	Yes

Keywords

Biodegradability
Block copolymer
L-lactide
Random copolymer
ε-caprolactone

Cite this

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title = "Synthesis and characterization of poly(L-lactide-co-ε-caprolactone) copolymers",

abstract = "A series of random and block poly(L-lactide-co-ε-caprolactone) (PCLA) copolymers with different composition are prepared using stannous octaoate as catalyst. The effects of the amount of initiator on the intrinsic viscosity have been investigated. The structure of the PCLA copolymers is characterized by means of nuclear magnetic resonance (NMR), Fourier transform, infrared spectrum (FTIR), differential scanning calorimetry (DSC) and X-ray diffraction (XRD) methods. It is shown that the synthesis condition and the composition of copolymers have obvious influence on the structure of PCLA copolymers. Hydrolytic degradation of the copolymers in a PBS solution of pH 7.4 at 37.0°C shows that the copolymers of different compositions degrade at different rates.",

keywords = "Biodegradability, Block copolymer, L-lactide, Random copolymer, ε-caprolactone",

author = "Xili Lu and Ye Wu and Wei Cai and Wenjun Tang",

year = "2005",

month = dec,

language = "英语",

volume = "20",

pages = "287--289",

journal = "Journal Wuhan University of Technology, Materials Science Edition",

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TY - JOUR

T1 - Synthesis and characterization of poly(L-lactide-co-ε-caprolactone) copolymers

AU - Lu, Xili

AU - Wu, Ye

AU - Cai, Wei

AU - Tang, Wenjun

PY - 2005/12

Y1 - 2005/12

N2 - A series of random and block poly(L-lactide-co-ε-caprolactone) (PCLA) copolymers with different composition are prepared using stannous octaoate as catalyst. The effects of the amount of initiator on the intrinsic viscosity have been investigated. The structure of the PCLA copolymers is characterized by means of nuclear magnetic resonance (NMR), Fourier transform, infrared spectrum (FTIR), differential scanning calorimetry (DSC) and X-ray diffraction (XRD) methods. It is shown that the synthesis condition and the composition of copolymers have obvious influence on the structure of PCLA copolymers. Hydrolytic degradation of the copolymers in a PBS solution of pH 7.4 at 37.0°C shows that the copolymers of different compositions degrade at different rates.

AB - A series of random and block poly(L-lactide-co-ε-caprolactone) (PCLA) copolymers with different composition are prepared using stannous octaoate as catalyst. The effects of the amount of initiator on the intrinsic viscosity have been investigated. The structure of the PCLA copolymers is characterized by means of nuclear magnetic resonance (NMR), Fourier transform, infrared spectrum (FTIR), differential scanning calorimetry (DSC) and X-ray diffraction (XRD) methods. It is shown that the synthesis condition and the composition of copolymers have obvious influence on the structure of PCLA copolymers. Hydrolytic degradation of the copolymers in a PBS solution of pH 7.4 at 37.0°C shows that the copolymers of different compositions degrade at different rates.

KW - Biodegradability

KW - Block copolymer

KW - L-lactide

KW - Random copolymer

KW - ε-caprolactone

UR - https://www.scopus.com/pages/publications/33646337435

M3 - 文章

AN - SCOPUS:33646337435

SN - 1000-2413

VL - 20

SP - 287

EP - 289

JO - Journal Wuhan University of Technology, Materials Science Edition

JF - Journal Wuhan University of Technology, Materials Science Edition

IS - SUPPL.

ER -

Synthesis and characterization of poly(L-lactide-co-ε-caprolactone) copolymers

Abstract

Keywords

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