Study on gout-specific local gene network and its relationship with nutrient metabolism modules

Chang Lu Guo; Cheng Li; Zhi Zhou Zhang

doi:10.1109/RSETE.2011.5966267

Study on gout-specific local gene network and its relationship with nutrient metabolism modules

Chang Lu Guo
, Cheng Li
, Zhi Zhou Zhang^*

^*Corresponding author for this work

Harbin Institute of Technology Weihai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

Gout has a high onset rate in coastal regions, and the interaction between gout susceptibility genes and (coastal) diet is needed to study. A molecular linkage between gout-specific local gene network (LGN) and nutrient metabolism modules was constructed based on a local gene network approach, which reveals a complex relationship between gout-specific-LGN and metabolic modules of nucleotide metabolism, lipid metabolism, amino acid metabolism, carbohydrate metabolism, cofactor and vitamin metabolism. Interestingly, nucleotide metabolism modules do link more gout genes than other metabolism modules, providing a primary technological platform to study the impact of diet on gout onset and to develop preventive personalized nutrition regimen.

Original language	English
Title of host publication	2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings
Pages	7886-7889
Number of pages	4
DOIs	https://doi.org/10.1109/RSETE.2011.5966267
State	Published - 2011
Externally published	Yes
Event	2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Nanjing, China Duration: 24 Jun 2011 → 26 Jun 2011

Publication series

Name	2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings

Conference

Conference	2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011
Country/Territory	China
City	Nanjing
Period	24/06/11 → 26/06/11

Keywords

Gout
Local gene network (LGN)
Nutrient metabolism modules

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10.1109/RSETE.2011.5966267

Cite this

Guo, C. L., Li, C., & Zhang, Z. Z. (2011). Study on gout-specific local gene network and its relationship with nutrient metabolism modules. In 2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings (pp. 7886-7889). Article 5966267 (2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings). https://doi.org/10.1109/RSETE.2011.5966267

Guo, Chang Lu ; Li, Cheng ; Zhang, Zhi Zhou. / Study on gout-specific local gene network and its relationship with nutrient metabolism modules. 2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings. 2011. pp. 7886-7889 (2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings).

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title = "Study on gout-specific local gene network and its relationship with nutrient metabolism modules",

abstract = "Gout has a high onset rate in coastal regions, and the interaction between gout susceptibility genes and (coastal) diet is needed to study. A molecular linkage between gout-specific local gene network (LGN) and nutrient metabolism modules was constructed based on a local gene network approach, which reveals a complex relationship between gout-specific-LGN and metabolic modules of nucleotide metabolism, lipid metabolism, amino acid metabolism, carbohydrate metabolism, cofactor and vitamin metabolism. Interestingly, nucleotide metabolism modules do link more gout genes than other metabolism modules, providing a primary technological platform to study the impact of diet on gout onset and to develop preventive personalized nutrition regimen.",

keywords = "Gout, Local gene network (LGN), Nutrient metabolism modules",

author = "Guo, \{Chang Lu\} and Cheng Li and Zhang, \{Zhi Zhou\}",

year = "2011",

doi = "10.1109/RSETE.2011.5966267",

language = "英语",

isbn = "9781424491711",

series = "2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings",

pages = "7886--7889",

booktitle = "2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings",

note = "2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 ; Conference date: 24-06-2011 Through 26-06-2011",

}

Guo, CL, Li, C & Zhang, ZZ 2011, Study on gout-specific local gene network and its relationship with nutrient metabolism modules. in 2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings., 5966267, 2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings, pp. 7886-7889, 2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011, Nanjing, China, 24/06/11. https://doi.org/10.1109/RSETE.2011.5966267

Study on gout-specific local gene network and its relationship with nutrient metabolism modules. / Guo, Chang Lu; Li, Cheng; Zhang, Zhi Zhou.
2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings. 2011. p. 7886-7889 5966267 (2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Li, Cheng

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N2 - Gout has a high onset rate in coastal regions, and the interaction between gout susceptibility genes and (coastal) diet is needed to study. A molecular linkage between gout-specific local gene network (LGN) and nutrient metabolism modules was constructed based on a local gene network approach, which reveals a complex relationship between gout-specific-LGN and metabolic modules of nucleotide metabolism, lipid metabolism, amino acid metabolism, carbohydrate metabolism, cofactor and vitamin metabolism. Interestingly, nucleotide metabolism modules do link more gout genes than other metabolism modules, providing a primary technological platform to study the impact of diet on gout onset and to develop preventive personalized nutrition regimen.

AB - Gout has a high onset rate in coastal regions, and the interaction between gout susceptibility genes and (coastal) diet is needed to study. A molecular linkage between gout-specific local gene network (LGN) and nutrient metabolism modules was constructed based on a local gene network approach, which reveals a complex relationship between gout-specific-LGN and metabolic modules of nucleotide metabolism, lipid metabolism, amino acid metabolism, carbohydrate metabolism, cofactor and vitamin metabolism. Interestingly, nucleotide metabolism modules do link more gout genes than other metabolism modules, providing a primary technological platform to study the impact of diet on gout onset and to develop preventive personalized nutrition regimen.

KW - Gout

KW - Local gene network (LGN)

KW - Nutrient metabolism modules

UR - https://www.scopus.com/pages/publications/80052213508

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DO - 10.1109/RSETE.2011.5966267

M3 - 会议稿件

AN - SCOPUS:80052213508

SN - 9781424491711

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BT - 2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings

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Y2 - 24 June 2011 through 26 June 2011

ER -

Guo CL, Li C, Zhang ZZ. Study on gout-specific local gene network and its relationship with nutrient metabolism modules. In 2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings. 2011. p. 7886-7889. 5966267. (2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings). doi: 10.1109/RSETE.2011.5966267

Study on gout-specific local gene network and its relationship with nutrient metabolism modules

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