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Simulation of effects of ischemia in 3D human ventricle

  • Harbin Institute of Technology
  • University of Manchester

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this paper, we present an integrated model of 3D human ventricle to simulate the effects of ischemia on wave propagation. To deal with the no-flux boundary conditions, a phase-field method is employed. The major advantage of the method is that it can automatically handle the boundary conditions. Through the increasing of concentration of extracellular K+ and ischemic size, the propagation of spiral wave under different ischemia symptoms is simulated. The experimental results show that with the increasing of ischemia severity and ischemic size, spiral waves are more and more instable, but when the tip of spiral wave stays inside the ischemic region, the spiral wave maintains stabilization.

Original languageEnglish
Title of host publicationComputers in Cardiology 2009, CinC 2009
PublisherIEEE Computer Society
Pages477-480
Number of pages4
ISBN (Print)9781424472819
StatePublished - 2009
Event36th Annual Conference of Computers in Cardiology, CinC 2009 - Park City, UT, United States
Duration: 13 Sep 200916 Sep 2009

Publication series

NameComputers in Cardiology
Volume36
ISSN (Print)0276-6574
ISSN (Electronic)2325-8853

Conference

Conference36th Annual Conference of Computers in Cardiology, CinC 2009
Country/TerritoryUnited States
CityPark City, UT
Period13/09/0916/09/09

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