Simulation of discrete blood vessel effects on the thermal signature of a melanoma lesion

Sri Kamal Kandala; Daxiang Deng; Cila Herman

doi:10.1115/IMECE2013-64451

Simulation of discrete blood vessel effects on the thermal signature of a melanoma lesion

Sri Kamal Kandala
, Daxiang Deng
, Cila Herman

Johns Hopkins University
South China University of Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

8 Scopus citations

Abstract

The effect of the underlying blood vessel on the transient thermal response of the skin surface with and without a melanoma lesion is studied. A 3D computational model of the layers of the skin tissue with cancerous lesion was developed in COMSOL software package. Heat transfer in the skin layers and the lesion is governed by the Pennes bio-heat equation, while the blood vessel is modeled as fully developed pipe flow with constant heat transfer coefficient. The effect of various pertinent parameters, such as diameter of the blood vessel, lateral location of the blood vessel relative to the lesion, flow velocity of the blood, on the skin surface temperature distribution, have been studied in the paper. The results show significant influence of the underlying blood vessel on the temperature of the skin surface and lesion as well as on the surrounding healthy tissue. Thus, a need for development of evaluation criteria for detection of malignant lesions in the presence of blood vessels is is discussed.

Original language	English
Title of host publication	Biomedical and Biotechnology Engineering
Publisher	American Society of Mechanical Engineers (ASME)
ISBN (Print)	9780791856222
DOIs	https://doi.org/10.1115/IMECE2013-64451
State	Published - 2013
Externally published	Yes
Event	ASME 2013 International Mechanical Engineering Congress and Exposition, IMECE 2013 - San Diego, CA, United States Duration: 15 Nov 2013 → 21 Nov 2013

Publication series

Name	ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volume	3 B

Conference

Conference	ASME 2013 International Mechanical Engineering Congress and Exposition, IMECE 2013
Country/Territory	United States
City	San Diego, CA
Period	15/11/13 → 21/11/13

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1115/IMECE2013-64451

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Kandala, S. K., Deng, D., & Herman, C. (2013). Simulation of discrete blood vessel effects on the thermal signature of a melanoma lesion. In Biomedical and Biotechnology Engineering (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); Vol. 3 B). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/IMECE2013-64451

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title = "Simulation of discrete blood vessel effects on the thermal signature of a melanoma lesion",

abstract = "The effect of the underlying blood vessel on the transient thermal response of the skin surface with and without a melanoma lesion is studied. A 3D computational model of the layers of the skin tissue with cancerous lesion was developed in COMSOL software package. Heat transfer in the skin layers and the lesion is governed by the Pennes bio-heat equation, while the blood vessel is modeled as fully developed pipe flow with constant heat transfer coefficient. The effect of various pertinent parameters, such as diameter of the blood vessel, lateral location of the blood vessel relative to the lesion, flow velocity of the blood, on the skin surface temperature distribution, have been studied in the paper. The results show significant influence of the underlying blood vessel on the temperature of the skin surface and lesion as well as on the surrounding healthy tissue. Thus, a need for development of evaluation criteria for detection of malignant lesions in the presence of blood vessels is is discussed.",

author = "Kandala, \{Sri Kamal\} and Daxiang Deng and Cila Herman",

year = "2013",

doi = "10.1115/IMECE2013-64451",

language = "英语",

isbn = "9780791856222",

series = "ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)",

publisher = "American Society of Mechanical Engineers (ASME)",

booktitle = "Biomedical and Biotechnology Engineering",

address = "美国",

note = "ASME 2013 International Mechanical Engineering Congress and Exposition, IMECE 2013 ; Conference date: 15-11-2013 Through 21-11-2013",

}

Kandala, SK, Deng, D & Herman, C 2013, Simulation of discrete blood vessel effects on the thermal signature of a melanoma lesion. in Biomedical and Biotechnology Engineering. ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE), vol. 3 B, American Society of Mechanical Engineers (ASME), ASME 2013 International Mechanical Engineering Congress and Exposition, IMECE 2013, San Diego, CA, United States, 15/11/13. https://doi.org/10.1115/IMECE2013-64451

Simulation of discrete blood vessel effects on the thermal signature of a melanoma lesion. / Kandala, Sri Kamal; Deng, Daxiang; Herman, Cila.
Biomedical and Biotechnology Engineering. American Society of Mechanical Engineers (ASME), 2013. (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); Vol. 3 B).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

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AU - Kandala, Sri Kamal

AU - Deng, Daxiang

AU - Herman, Cila

PY - 2013

Y1 - 2013

N2 - The effect of the underlying blood vessel on the transient thermal response of the skin surface with and without a melanoma lesion is studied. A 3D computational model of the layers of the skin tissue with cancerous lesion was developed in COMSOL software package. Heat transfer in the skin layers and the lesion is governed by the Pennes bio-heat equation, while the blood vessel is modeled as fully developed pipe flow with constant heat transfer coefficient. The effect of various pertinent parameters, such as diameter of the blood vessel, lateral location of the blood vessel relative to the lesion, flow velocity of the blood, on the skin surface temperature distribution, have been studied in the paper. The results show significant influence of the underlying blood vessel on the temperature of the skin surface and lesion as well as on the surrounding healthy tissue. Thus, a need for development of evaluation criteria for detection of malignant lesions in the presence of blood vessels is is discussed.

AB - The effect of the underlying blood vessel on the transient thermal response of the skin surface with and without a melanoma lesion is studied. A 3D computational model of the layers of the skin tissue with cancerous lesion was developed in COMSOL software package. Heat transfer in the skin layers and the lesion is governed by the Pennes bio-heat equation, while the blood vessel is modeled as fully developed pipe flow with constant heat transfer coefficient. The effect of various pertinent parameters, such as diameter of the blood vessel, lateral location of the blood vessel relative to the lesion, flow velocity of the blood, on the skin surface temperature distribution, have been studied in the paper. The results show significant influence of the underlying blood vessel on the temperature of the skin surface and lesion as well as on the surrounding healthy tissue. Thus, a need for development of evaluation criteria for detection of malignant lesions in the presence of blood vessels is is discussed.

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DO - 10.1115/IMECE2013-64451

M3 - 会议稿件

AN - SCOPUS:84903465996

SN - 9780791856222

T3 - ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)

BT - Biomedical and Biotechnology Engineering

PB - American Society of Mechanical Engineers (ASME)

T2 - ASME 2013 International Mechanical Engineering Congress and Exposition, IMECE 2013

Y2 - 15 November 2013 through 21 November 2013

ER -

Simulation of discrete blood vessel effects on the thermal signature of a melanoma lesion

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