Regioselective synthesis of gentisyl alcohol-type marine natural products

Hong Shuang Wang; Hui Jing Li; Long Fei Wang; Zhi Lun Shen; Yan Chao Wu

doi:10.1080/14786419.2018.1478831

Regioselective synthesis of gentisyl alcohol-type marine natural products

Hong Shuang Wang
, Hui Jing Li^*
, Long Fei Wang
, Zhi Lun Shen
, Yan Chao Wu

^*Corresponding author for this work

School of Marine Science and Technology, Harbin Institute of Technology Weihai
CAS - Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Gentisyl alcohol-type natural products, possessing various important biological properties, have been synthesized from 4-methoxyphenol by using a selective phenol monohydroxymethylation/monochlorination, a CAN oxidation and a sodium dithionite reduction as the key steps. The natural product synthesis is efficient, atom- and step-economical, and requires no protecting groups.

Original language	English
Pages (from-to)	1891-1896
Number of pages	6
Journal	Natural Product Research
Volume	33
Issue number	13
DOIs	https://doi.org/10.1080/14786419.2018.1478831
State	Published - 3 Jul 2019
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 14 Life Below Water

Keywords

Natural products
chlorination
chlorogentisyl alcohol
gentisyl alcohol
hydroxymethylation
synthesis

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10.1080/14786419.2018.1478831

Cite this

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title = "Regioselective synthesis of gentisyl alcohol-type marine natural products",

abstract = "Gentisyl alcohol-type natural products, possessing various important biological properties, have been synthesized from 4-methoxyphenol by using a selective phenol monohydroxymethylation/monochlorination, a CAN oxidation and a sodium dithionite reduction as the key steps. The natural product synthesis is efficient, atom- and step-economical, and requires no protecting groups.",

keywords = "Natural products, chlorination, chlorogentisyl alcohol, gentisyl alcohol, hydroxymethylation, synthesis",

author = "Wang, \{Hong Shuang\} and Li, \{Hui Jing\} and Wang, \{Long Fei\} and Shen, \{Zhi Lun\} and Wu, \{Yan Chao\}",

note = "Publisher Copyright: {\textcopyright} 2018, {\textcopyright} 2018 Informa UK Limited, trading as Taylor \& Francis Group.",

year = "2019",

month = jul,

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doi = "10.1080/14786419.2018.1478831",

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journal = "Natural Product Research",

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T1 - Regioselective synthesis of gentisyl alcohol-type marine natural products

AU - Wang, Hong Shuang

AU - Li, Hui Jing

AU - Wang, Long Fei

AU - Shen, Zhi Lun

AU - Wu, Yan Chao

PY - 2019/7/3

Y1 - 2019/7/3

N2 - Gentisyl alcohol-type natural products, possessing various important biological properties, have been synthesized from 4-methoxyphenol by using a selective phenol monohydroxymethylation/monochlorination, a CAN oxidation and a sodium dithionite reduction as the key steps. The natural product synthesis is efficient, atom- and step-economical, and requires no protecting groups.

AB - Gentisyl alcohol-type natural products, possessing various important biological properties, have been synthesized from 4-methoxyphenol by using a selective phenol monohydroxymethylation/monochlorination, a CAN oxidation and a sodium dithionite reduction as the key steps. The natural product synthesis is efficient, atom- and step-economical, and requires no protecting groups.

KW - Natural products

KW - chlorination

KW - chlorogentisyl alcohol

KW - gentisyl alcohol

KW - hydroxymethylation

KW - synthesis

UR - https://www.scopus.com/pages/publications/85047415437

U2 - 10.1080/14786419.2018.1478831

DO - 10.1080/14786419.2018.1478831

M3 - 文章

C2 - 29798697

AN - SCOPUS:85047415437

SN - 1478-6419

VL - 33

SP - 1891

EP - 1896

JO - Natural Product Research

JF - Natural Product Research

IS - 13

ER -

Regioselective synthesis of gentisyl alcohol-type marine natural products

Abstract

UN SDGs

Keywords

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