Abstract
A divergent and expeditious access to haterumadienone- and puupehenone-type marine natural products has been achieved by using a newly developed hemiacetalization/dehydroxylation/hydroxylation/retro-hemiacetalization tandem reaction as one of the key steps. Its applicability is showcased by the first synthesis of haterumadienone, 20-hydroxyhaterumadienone, 20-epihydroxy-haterumadienone and 20-acetoxy-haterumadienone, as well as the facile synthesis of puupehenone, puupehedione and puupehenol. The synthesis is efficient, and atom- and step-economical (6 to 9 steps from commercially available starting materials), and requires no protecting groups and transition metals.
| Original language | English |
|---|---|
| Pages (from-to) | 2140-2144 |
| Number of pages | 5 |
| Journal | Green Chemistry |
| Volume | 19 |
| Issue number | 9 |
| DOIs | |
| State | Published - 2017 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 14 Life Below Water
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