Progress and prospects of long noncoding RNAs in lipid homeostasis

Zheng Chen

doi:10.1016/j.molmet.2015.12.003

Progress and prospects of long noncoding RNAs in lipid homeostasis

Zheng Chen^*

^*Corresponding author for this work

Northeast Normal University

Research output: Contribution to journal › Review article › peer-review

79 Scopus citations

Abstract

Background: Long noncoding RNAs (lncRNAs) are a novel group of universally present, non-coding RNAs (>200 nt) that are increasingly recognized as key regulators of many physiological and pathological processes. Scope of review: Recent publications have shown that lncRNAs influence lipid homeostasis by controlling lipid metabolism in the liver and by regulating adipogenesis. lncRNAs control lipid metabolism-related gene expression by either base-pairing with RNA and DNA or by binding to proteins. Major conclusions: The recent advances and future prospects in understanding the roles of lncRNAs in lipid homeostasis are discussed.

Original language	English
Pages (from-to)	164-170
Number of pages	7
Journal	Molecular Metabolism
Volume	5
Issue number	3
DOIs	https://doi.org/10.1016/j.molmet.2015.12.003
State	Published - 1 Mar 2016
Externally published	Yes

Keywords

Adipogenesis
Adipose tissue
Lipid metabolism
Liver
LncRNA

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10.1016/j.molmet.2015.12.003

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title = "Progress and prospects of long noncoding RNAs in lipid homeostasis",

abstract = "Background: Long noncoding RNAs (lncRNAs) are a novel group of universally present, non-coding RNAs (>200 nt) that are increasingly recognized as key regulators of many physiological and pathological processes. Scope of review: Recent publications have shown that lncRNAs influence lipid homeostasis by controlling lipid metabolism in the liver and by regulating adipogenesis. lncRNAs control lipid metabolism-related gene expression by either base-pairing with RNA and DNA or by binding to proteins. Major conclusions: The recent advances and future prospects in understanding the roles of lncRNAs in lipid homeostasis are discussed.",

keywords = "Adipogenesis, Adipose tissue, Lipid metabolism, Liver, LncRNA",

author = "Zheng Chen",

note = "Publisher Copyright: {\textcopyright} 2015 The Author.",

year = "2016",

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doi = "10.1016/j.molmet.2015.12.003",

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AU - Chen, Zheng

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Background: Long noncoding RNAs (lncRNAs) are a novel group of universally present, non-coding RNAs (>200 nt) that are increasingly recognized as key regulators of many physiological and pathological processes. Scope of review: Recent publications have shown that lncRNAs influence lipid homeostasis by controlling lipid metabolism in the liver and by regulating adipogenesis. lncRNAs control lipid metabolism-related gene expression by either base-pairing with RNA and DNA or by binding to proteins. Major conclusions: The recent advances and future prospects in understanding the roles of lncRNAs in lipid homeostasis are discussed.

AB - Background: Long noncoding RNAs (lncRNAs) are a novel group of universally present, non-coding RNAs (>200 nt) that are increasingly recognized as key regulators of many physiological and pathological processes. Scope of review: Recent publications have shown that lncRNAs influence lipid homeostasis by controlling lipid metabolism in the liver and by regulating adipogenesis. lncRNAs control lipid metabolism-related gene expression by either base-pairing with RNA and DNA or by binding to proteins. Major conclusions: The recent advances and future prospects in understanding the roles of lncRNAs in lipid homeostasis are discussed.

KW - Adipogenesis

KW - Adipose tissue

KW - Lipid metabolism

KW - Liver

KW - LncRNA

UR - https://www.scopus.com/pages/publications/84959087775

U2 - 10.1016/j.molmet.2015.12.003

DO - 10.1016/j.molmet.2015.12.003

M3 - 文献综述

AN - SCOPUS:84959087775

SN - 2212-8778

VL - 5

SP - 164

EP - 170

JO - Molecular Metabolism

JF - Molecular Metabolism

IS - 3

ER -

Progress and prospects of long noncoding RNAs in lipid homeostasis

Abstract

Keywords

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