Progress and developments in the turbo Grignard reagent i-PrMgCl·LiCl: A ten-year journey

Robert Li-Yuan Bao; Rong Zhao; Lei Shi

doi:10.1039/c4cc10194d

Progress and developments in the turbo Grignard reagent i-PrMgCl·LiCl: A ten-year journey

Robert Li-Yuan Bao
, Rong Zhao
, Lei Shi^*

^*Corresponding author for this work

School of Sciences

Harbin Institute of Technology

Research output: Contribution to journal › Article › peer-review

155 Scopus citations

Abstract

Over the past decade, the effectiveness of i-PrMgCl·LiCl has been constantly highlighted by a number of research groups. Its enhanced nucleophilicity brings prosperity to highly functionalized Grignard reagents, other useful bimetallic (alkali-metal) agents and nucleophilic alkylation products under mild reaction conditions. In this feature article, a comprehensive, systematical and in-depth overview of i-PrMgCl·LiCl is provided in a multidisciplinary idea. It involves the structural and kinetic perspectives of i-PrMgCl·LiCl as well as its unique reactivity and selectivity, with knowledge of the former helping to rationalize trends of the later.

Original language	English
Pages (from-to)	6884-6900
Number of pages	17
Journal	Chemical Communications
Volume	51
Issue number	32
DOIs	https://doi.org/10.1039/c4cc10194d
State	Published - 25 Apr 2015

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title = "Progress and developments in the turbo Grignard reagent i-PrMgCl·LiCl: A ten-year journey",

abstract = "Over the past decade, the effectiveness of i-PrMgCl·LiCl has been constantly highlighted by a number of research groups. Its enhanced nucleophilicity brings prosperity to highly functionalized Grignard reagents, other useful bimetallic (alkali-metal) agents and nucleophilic alkylation products under mild reaction conditions. In this feature article, a comprehensive, systematical and in-depth overview of i-PrMgCl·LiCl is provided in a multidisciplinary idea. It involves the structural and kinetic perspectives of i-PrMgCl·LiCl as well as its unique reactivity and selectivity, with knowledge of the former helping to rationalize trends of the later.",

author = "\{Li-Yuan Bao\}, Robert and Rong Zhao and Lei Shi",

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doi = "10.1039/c4cc10194d",

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T1 - Progress and developments in the turbo Grignard reagent i-PrMgCl·LiCl

T2 - A ten-year journey

AU - Li-Yuan Bao, Robert

AU - Zhao, Rong

AU - Shi, Lei

PY - 2015/4/25

Y1 - 2015/4/25

N2 - Over the past decade, the effectiveness of i-PrMgCl·LiCl has been constantly highlighted by a number of research groups. Its enhanced nucleophilicity brings prosperity to highly functionalized Grignard reagents, other useful bimetallic (alkali-metal) agents and nucleophilic alkylation products under mild reaction conditions. In this feature article, a comprehensive, systematical and in-depth overview of i-PrMgCl·LiCl is provided in a multidisciplinary idea. It involves the structural and kinetic perspectives of i-PrMgCl·LiCl as well as its unique reactivity and selectivity, with knowledge of the former helping to rationalize trends of the later.

AB - Over the past decade, the effectiveness of i-PrMgCl·LiCl has been constantly highlighted by a number of research groups. Its enhanced nucleophilicity brings prosperity to highly functionalized Grignard reagents, other useful bimetallic (alkali-metal) agents and nucleophilic alkylation products under mild reaction conditions. In this feature article, a comprehensive, systematical and in-depth overview of i-PrMgCl·LiCl is provided in a multidisciplinary idea. It involves the structural and kinetic perspectives of i-PrMgCl·LiCl as well as its unique reactivity and selectivity, with knowledge of the former helping to rationalize trends of the later.

UR - https://www.scopus.com/pages/publications/84926629964

U2 - 10.1039/c4cc10194d

DO - 10.1039/c4cc10194d

M3 - 文章

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SN - 1359-7345

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SP - 6884

EP - 6900

JO - Chemical Communications

JF - Chemical Communications

IS - 32

ER -

Progress and developments in the turbo Grignard reagent i-PrMgCl·LiCl: A ten-year journey

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