Preliminary Study of Local Gene Network in Epilepsy

Tianhe Zhang; Le Ao; Bo Sun; Chuyi Zhang; Wenqing Su; Xingfeng Du; Changlu Guo; Yu Yang

doi:10.1145/3469678.3469688

^*Corresponding author for this work

School of Marine Science and Technology, Harbin Institute of Technology Weihai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

This research taking epilepsy as the research object, uses network database resources to inquire and sort out the relevant genes, and uses the biological pathways involved in genes to successfully construct a local gene network. The coupling of the metabolic module proves that there is a complex connection between epilepsy and the nutritional metabolism module. To a certain extent, it reflects the important influence of nutritional metabolism on epilepsy, and also provides a basis for the prevention and treatment of epilepsy through diet and the development of new therapeutic drugs.

Original language	English
Title of host publication	Proceedings of the 5th International Conference on Biological Information and Biomedical Engineering, BIBE 2021
Editors	Bin Chen
Publisher	Association for Computing Machinery
ISBN (Electronic)	9781450389297
DOIs	https://doi.org/10.1145/3469678.3469688
State	Published - 20 Jul 2021
Externally published	Yes
Event	5th International Conference on Biological Information and Biomedical Engineering, BIBE 2021 - Hangzhou, China Duration: 20 Jul 2021 → 21 Jul 2021

Publication series

Name	ACM International Conference Proceeding Series

Conference

Conference	5th International Conference on Biological Information and Biomedical Engineering, BIBE 2021
Country/Territory	China
City	Hangzhou
Period	20/07/21 → 21/07/21

Keywords

Epilepsy
Local gene network (LGN)
Nutrient metabolism modules

Access to Document

10.1145/3469678.3469688

Cite this

Zhang, T., Ao, L., Sun, B., Zhang, C., Su, W., Du, X., Guo, C., & Yang, Y. (2021). Preliminary Study of Local Gene Network in Epilepsy. In B. Chen (Ed.), Proceedings of the 5th International Conference on Biological Information and Biomedical Engineering, BIBE 2021 Article 3469688 (ACM International Conference Proceeding Series). Association for Computing Machinery . https://doi.org/10.1145/3469678.3469688

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title = "Preliminary Study of Local Gene Network in Epilepsy",

abstract = "This research taking epilepsy as the research object, uses network database resources to inquire and sort out the relevant genes, and uses the biological pathways involved in genes to successfully construct a local gene network. The coupling of the metabolic module proves that there is a complex connection between epilepsy and the nutritional metabolism module. To a certain extent, it reflects the important influence of nutritional metabolism on epilepsy, and also provides a basis for the prevention and treatment of epilepsy through diet and the development of new therapeutic drugs.",

keywords = "Epilepsy, Local gene network (LGN), Nutrient metabolism modules",

author = "Tianhe Zhang and Le Ao and Bo Sun and Chuyi Zhang and Wenqing Su and Xingfeng Du and Changlu Guo and Yu Yang",

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Zhang, T, Ao, L, Sun, B, Zhang, C, Su, W, Du, X, Guo, C & Yang, Y 2021, Preliminary Study of Local Gene Network in Epilepsy. in B Chen (ed.), Proceedings of the 5th International Conference on Biological Information and Biomedical Engineering, BIBE 2021., 3469688, ACM International Conference Proceeding Series, Association for Computing Machinery , 5th International Conference on Biological Information and Biomedical Engineering, BIBE 2021, Hangzhou, China, 20/07/21. https://doi.org/10.1145/3469678.3469688

Preliminary Study of Local Gene Network in Epilepsy. / Zhang, Tianhe; Ao, Le; Sun, Bo et al.
Proceedings of the 5th International Conference on Biological Information and Biomedical Engineering, BIBE 2021. ed. / Bin Chen. Association for Computing Machinery , 2021. 3469688 (ACM International Conference Proceeding Series).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Zhang, Tianhe

AU - Ao, Le

AU - Sun, Bo

AU - Zhang, Chuyi

AU - Su, Wenqing

AU - Du, Xingfeng

AU - Guo, Changlu

AU - Yang, Yu

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N2 - This research taking epilepsy as the research object, uses network database resources to inquire and sort out the relevant genes, and uses the biological pathways involved in genes to successfully construct a local gene network. The coupling of the metabolic module proves that there is a complex connection between epilepsy and the nutritional metabolism module. To a certain extent, it reflects the important influence of nutritional metabolism on epilepsy, and also provides a basis for the prevention and treatment of epilepsy through diet and the development of new therapeutic drugs.

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KW - Local gene network (LGN)

KW - Nutrient metabolism modules

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