Portable microscopy platform for the clinical and environmental monitoring

Weiming Wang; Yan Yu; Hui Huang; Jinping Ou

doi:10.1117/12.2219114

Portable microscopy platform for the clinical and environmental monitoring

Weiming Wang
, Yan Yu
, Hui Huang
, Jinping Ou

Dalian University of Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Scopus citations

Abstract

Light microscopy can not only address various diagnosis needs such as aquatic parasites and bacteria such as E. coli in water, but also provide a method for the screening of red tide. Traditional microscope based on the smartphone created by adding lens couldn't keep the tradeoff between field-of-view(FOV) and the resolution. In this paper, we demonstrate a non-contact, light and cost-effective microscope platform, that can image highly dense samples with a spatial resolution of ∼0.8um over a field-of-view(FOV) of >1mm². After captured the direct images, we performed the pixel super-resolution algorithm to improve the image resolution and overcome the hardware interference. The system would be a good point-of-care diagnostic solution in resource limited settings. We validated the performance of the system by imaging resolution test targets, the squamous cell cancer(SqCC) and green algae that necessary to detect the squamous carcinoma and red tide.

Original language	English
Title of host publication	Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016
Editors	Vijay K. Varadan
Publisher	SPIE
ISBN (Electronic)	9781510600430
DOIs	https://doi.org/10.1117/12.2219114
State	Published - 2016
Externally published	Yes
Event	Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016 - Las Vegas, United States Duration: 21 Mar 2016 → 24 Mar 2016

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	9802
ISSN (Print)	0277-786X
ISSN (Electronic)	1996-756X

Conference

Conference	Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016
Country/Territory	United States
City	Las Vegas
Period	21/03/16 → 24/03/16

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Pixel super-resolution
Portable microscope platform
Red tide
SqCC
Telemedicine

Access to Document

10.1117/12.2219114

Cite this

@inproceedings{7fc89153e7b945c2b230036ea57bda73,

title = "Portable microscopy platform for the clinical and environmental monitoring",

abstract = "Light microscopy can not only address various diagnosis needs such as aquatic parasites and bacteria such as E. coli in water, but also provide a method for the screening of red tide. Traditional microscope based on the smartphone created by adding lens couldn't keep the tradeoff between field-of-view(FOV) and the resolution. In this paper, we demonstrate a non-contact, light and cost-effective microscope platform, that can image highly dense samples with a spatial resolution of ∼0.8um over a field-of-view(FOV) of >1mm2. After captured the direct images, we performed the pixel super-resolution algorithm to improve the image resolution and overcome the hardware interference. The system would be a good point-of-care diagnostic solution in resource limited settings. We validated the performance of the system by imaging resolution test targets, the squamous cell cancer(SqCC) and green algae that necessary to detect the squamous carcinoma and red tide.",

keywords = "Pixel super-resolution, Portable microscope platform, Red tide, SqCC, Telemedicine",

author = "Weiming Wang and Yan Yu and Hui Huang and Jinping Ou",

note = "Publisher Copyright: {\textcopyright} 2016 SPIE.; Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016 ; Conference date: 21-03-2016 Through 24-03-2016",

year = "2016",

doi = "10.1117/12.2219114",

language = "英语",

series = "Proceedings of SPIE - The International Society for Optical Engineering",

publisher = "SPIE",

editor = "Varadan, \{Vijay K.\}",

booktitle = "Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016",

address = "美国",

}

Wang, W, Yu, Y, Huang, H & Ou, J 2016, Portable microscopy platform for the clinical and environmental monitoring. in VK Varadan (ed.), Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016., 98021P, Proceedings of SPIE - The International Society for Optical Engineering, vol. 9802, SPIE, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016, Las Vegas, United States, 21/03/16. https://doi.org/10.1117/12.2219114

Portable microscopy platform for the clinical and environmental monitoring. / Wang, Weiming; Yu, Yan; Huang, Hui et al.
Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016. ed. / Vijay K. Varadan. SPIE, 2016. 98021P (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 9802).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Portable microscopy platform for the clinical and environmental monitoring

AU - Wang, Weiming

AU - Yu, Yan

AU - Huang, Hui

AU - Ou, Jinping

PY - 2016

Y1 - 2016

N2 - Light microscopy can not only address various diagnosis needs such as aquatic parasites and bacteria such as E. coli in water, but also provide a method for the screening of red tide. Traditional microscope based on the smartphone created by adding lens couldn't keep the tradeoff between field-of-view(FOV) and the resolution. In this paper, we demonstrate a non-contact, light and cost-effective microscope platform, that can image highly dense samples with a spatial resolution of ∼0.8um over a field-of-view(FOV) of >1mm2. After captured the direct images, we performed the pixel super-resolution algorithm to improve the image resolution and overcome the hardware interference. The system would be a good point-of-care diagnostic solution in resource limited settings. We validated the performance of the system by imaging resolution test targets, the squamous cell cancer(SqCC) and green algae that necessary to detect the squamous carcinoma and red tide.

AB - Light microscopy can not only address various diagnosis needs such as aquatic parasites and bacteria such as E. coli in water, but also provide a method for the screening of red tide. Traditional microscope based on the smartphone created by adding lens couldn't keep the tradeoff between field-of-view(FOV) and the resolution. In this paper, we demonstrate a non-contact, light and cost-effective microscope platform, that can image highly dense samples with a spatial resolution of ∼0.8um over a field-of-view(FOV) of >1mm2. After captured the direct images, we performed the pixel super-resolution algorithm to improve the image resolution and overcome the hardware interference. The system would be a good point-of-care diagnostic solution in resource limited settings. We validated the performance of the system by imaging resolution test targets, the squamous cell cancer(SqCC) and green algae that necessary to detect the squamous carcinoma and red tide.

KW - Pixel super-resolution

KW - Portable microscope platform

KW - Red tide

KW - SqCC

KW - Telemedicine

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DO - 10.1117/12.2219114

M3 - 会议稿件

AN - SCOPUS:84989872147

T3 - Proceedings of SPIE - The International Society for Optical Engineering

BT - Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016

A2 - Varadan, Vijay K.

PB - SPIE

T2 - Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016

Y2 - 21 March 2016 through 24 March 2016

ER -

Portable microscopy platform for the clinical and environmental monitoring

Abstract

Publication series

Conference

UN SDGs

Keywords

Access to Document

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