Nonfouling polyampholytes from an ion-pair comonomer with biomimetic adhesive groups

Guozhu Li; Hong Xue; Changlu Gao; Fengbao Zhang; Shaoyi Jiang

doi:10.1021/ma902029s

Nonfouling polyampholytes from an ion-pair comonomer with biomimetic adhesive groups

Guozhu Li
, Hong Xue
, Changlu Gao
, Fengbao Zhang
, Shaoyi Jiang^*

^*Corresponding author for this work

University of Washington
Tianjin University

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Abstract

Two adhesive polyampholytes were synthesized by the polymerization of an ion-pair comonomer using two types of catecholic initiators. The molecular weight and polydispersity index (PDI) of the polyampholytes were determined by using an aqueous gel permeation chromatography (GPC). The film thickness of the polymers attached on surfaces was measured by an ellipsometer. Attenuated total reflectance Fourier transform infrared (ATR-FTIR) was used to monitor functional groups on the surface qualitatively. Electron spectroscopy for chemical analysis (ESCA) was employed to determine the surface composition quantitatively. The protein-resistant properties were determined by measuring protein adsorption from fibrinogen (Fg), lysozyme (Lyz), and bovine serum albumin (BSA) using a surface plasmon resonance (SPR) sensor. These neutral charged surfaces give excellent nonfouling properties from protein solutions of Fg, Lyz, and BSA.

Original language	English
Pages (from-to)	14-16
Number of pages	3
Journal	Macromolecules
Volume	43
Issue number	1
DOIs	https://doi.org/10.1021/ma902029s
State	Published - 12 Jan 2010
Externally published	Yes

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title = "Nonfouling polyampholytes from an ion-pair comonomer with biomimetic adhesive groups",

abstract = "Two adhesive polyampholytes were synthesized by the polymerization of an ion-pair comonomer using two types of catecholic initiators. The molecular weight and polydispersity index (PDI) of the polyampholytes were determined by using an aqueous gel permeation chromatography (GPC). The film thickness of the polymers attached on surfaces was measured by an ellipsometer. Attenuated total reflectance Fourier transform infrared (ATR-FTIR) was used to monitor functional groups on the surface qualitatively. Electron spectroscopy for chemical analysis (ESCA) was employed to determine the surface composition quantitatively. The protein-resistant properties were determined by measuring protein adsorption from fibrinogen (Fg), lysozyme (Lyz), and bovine serum albumin (BSA) using a surface plasmon resonance (SPR) sensor. These neutral charged surfaces give excellent nonfouling properties from protein solutions of Fg, Lyz, and BSA.",

author = "Guozhu Li and Hong Xue and Changlu Gao and Fengbao Zhang and Shaoyi Jiang",

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T1 - Nonfouling polyampholytes from an ion-pair comonomer with biomimetic adhesive groups

AU - Li, Guozhu

AU - Xue, Hong

AU - Gao, Changlu

AU - Zhang, Fengbao

AU - Jiang, Shaoyi

PY - 2010/1/12

Y1 - 2010/1/12

N2 - Two adhesive polyampholytes were synthesized by the polymerization of an ion-pair comonomer using two types of catecholic initiators. The molecular weight and polydispersity index (PDI) of the polyampholytes were determined by using an aqueous gel permeation chromatography (GPC). The film thickness of the polymers attached on surfaces was measured by an ellipsometer. Attenuated total reflectance Fourier transform infrared (ATR-FTIR) was used to monitor functional groups on the surface qualitatively. Electron spectroscopy for chemical analysis (ESCA) was employed to determine the surface composition quantitatively. The protein-resistant properties were determined by measuring protein adsorption from fibrinogen (Fg), lysozyme (Lyz), and bovine serum albumin (BSA) using a surface plasmon resonance (SPR) sensor. These neutral charged surfaces give excellent nonfouling properties from protein solutions of Fg, Lyz, and BSA.

AB - Two adhesive polyampholytes were synthesized by the polymerization of an ion-pair comonomer using two types of catecholic initiators. The molecular weight and polydispersity index (PDI) of the polyampholytes were determined by using an aqueous gel permeation chromatography (GPC). The film thickness of the polymers attached on surfaces was measured by an ellipsometer. Attenuated total reflectance Fourier transform infrared (ATR-FTIR) was used to monitor functional groups on the surface qualitatively. Electron spectroscopy for chemical analysis (ESCA) was employed to determine the surface composition quantitatively. The protein-resistant properties were determined by measuring protein adsorption from fibrinogen (Fg), lysozyme (Lyz), and bovine serum albumin (BSA) using a surface plasmon resonance (SPR) sensor. These neutral charged surfaces give excellent nonfouling properties from protein solutions of Fg, Lyz, and BSA.

UR - https://www.scopus.com/pages/publications/73649140929

U2 - 10.1021/ma902029s

DO - 10.1021/ma902029s

M3 - 文章

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SN - 0024-9297

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SP - 14

EP - 16

JO - Macromolecules

JF - Macromolecules

IS - 1

ER -

Nonfouling polyampholytes from an ion-pair comonomer with biomimetic adhesive groups

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