Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C-O Bond Cleavage

Huifeng Yue; Lin Guo; Xiangqian Liu; Magnus Rueping

doi:10.1021/acs.orglett.7b00556

Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C-O Bond Cleavage

Huifeng Yue
, Lin Guo
, Xiangqian Liu
, Magnus Rueping^*

^*Corresponding author for this work

RWTH Aachen University
King Abdullah University of Science and Technology

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp²)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.

Original language	English
Pages (from-to)	1788-1791
Number of pages	4
Journal	Organic Letters
Volume	19
Issue number	7
DOIs	https://doi.org/10.1021/acs.orglett.7b00556
State	Published - 7 Apr 2017
Externally published	Yes

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title = "Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C-O Bond Cleavage",

abstract = "A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.",

author = "Huifeng Yue and Lin Guo and Xiangqian Liu and Magnus Rueping",

note = "Publisher Copyright: {\textcopyright} 2017 American Chemical Society.",

year = "2017",

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doi = "10.1021/acs.orglett.7b00556",

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T1 - Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C-O Bond Cleavage

AU - Yue, Huifeng

AU - Guo, Lin

AU - Liu, Xiangqian

AU - Rueping, Magnus

PY - 2017/4/7

Y1 - 2017/4/7

N2 - A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.

AB - A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.

UR - https://www.scopus.com/pages/publications/85017103512

U2 - 10.1021/acs.orglett.7b00556

DO - 10.1021/acs.orglett.7b00556

M3 - 文章

C2 - 28287744

AN - SCOPUS:85017103512

SN - 1523-7060

VL - 19

SP - 1788

EP - 1791

JO - Organic Letters

JF - Organic Letters

IS - 7

ER -

Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C-O Bond Cleavage

Abstract

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