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Nickel-catalyzed: Exo -selective hydroacylation/Suzuki cross-coupling reaction

  • Shao Chi Lee
  • , Lin Guo
  • , Magnus Rueping*
  • *Corresponding author for this work
  • RWTH Aachen University
  • King Abdullah University of Science and Technology

Research output: Contribution to journalArticlepeer-review

Abstract

The first nickel-catalyzed intramolecular hydroacylation/Suzuki cross coupling cascade of o-allylbenzaldehydes with a broad range of phenylboronic acid neopentyl glycol esters has been developed. This strategy shows high regioselectivity and step economy in the construction of two C-C bonds via aldehyde C-H bond activation, affording valuable indanones with high efficiency.

Original languageEnglish
Pages (from-to)14984-14987
Number of pages4
JournalChemical Communications
Volume55
Issue number99
DOIs
StatePublished - 2019
Externally publishedYes

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