Ni-catalyzed reductive allylation of unactivated alkyl halides with allylic carbonates

Yijing Dai; Fan Wu; Zhenhua Zang; Hengzhi You; Hegui Gong

doi:10.1002/chem.201102984

Ni-catalyzed reductive allylation of unactivated alkyl halides with allylic carbonates

Yijing Dai
, Fan Wu
, Zhenhua Zang
, Hengzhi You
, Hegui Gong^*

^*Corresponding author for this work

Shanghai University

Research output: Contribution to journal › Article › peer-review

110 Scopus citations

Abstract

Game of two electrophiles: Two partially positively charged sp ³ carbon atoms can be connected by using a catalytic Ni species in the presence of an environmentally benign Zn reductant, delivering allylated alkanes (see scheme). This unprecedented approach allowed a variety of unactivated alkyl halides and substituted allylic carbonates to regioselectively afford E-alkenes in good to excellent yields.

Original language	English
Pages (from-to)	808-812
Number of pages	5
Journal	Chemistry - A European Journal
Volume	18
Issue number	3
DOIs	https://doi.org/10.1002/chem.201102984
State	Published - 16 Jan 2012
Externally published	Yes

Keywords

alkyl halides
allylation
allylic compounds
nickel
reductive coupling

Access to Document

10.1002/chem.201102984

Cite this

@article{cf5fc0f1dd224ecdb0809b3b0bab153e,

title = "Ni-catalyzed reductive allylation of unactivated alkyl halides with allylic carbonates",

abstract = "Game of two electrophiles: Two partially positively charged sp 3 carbon atoms can be connected by using a catalytic Ni species in the presence of an environmentally benign Zn reductant, delivering allylated alkanes (see scheme). This unprecedented approach allowed a variety of unactivated alkyl halides and substituted allylic carbonates to regioselectively afford E-alkenes in good to excellent yields.",

keywords = "alkyl halides, allylation, allylic compounds, nickel, reductive coupling",

author = "Yijing Dai and Fan Wu and Zhenhua Zang and Hengzhi You and Hegui Gong",

year = "2012",

month = jan,

day = "16",

doi = "10.1002/chem.201102984",

language = "英语",

volume = "18",

pages = "808--812",

journal = "Chemistry - A European Journal",

issn = "0947-6539",

publisher = "John Wiley and Sons Inc",

number = "3",

}

TY - JOUR

T1 - Ni-catalyzed reductive allylation of unactivated alkyl halides with allylic carbonates

AU - Dai, Yijing

AU - Wu, Fan

AU - Zang, Zhenhua

AU - You, Hengzhi

AU - Gong, Hegui

PY - 2012/1/16

Y1 - 2012/1/16

N2 - Game of two electrophiles: Two partially positively charged sp 3 carbon atoms can be connected by using a catalytic Ni species in the presence of an environmentally benign Zn reductant, delivering allylated alkanes (see scheme). This unprecedented approach allowed a variety of unactivated alkyl halides and substituted allylic carbonates to regioselectively afford E-alkenes in good to excellent yields.

AB - Game of two electrophiles: Two partially positively charged sp 3 carbon atoms can be connected by using a catalytic Ni species in the presence of an environmentally benign Zn reductant, delivering allylated alkanes (see scheme). This unprecedented approach allowed a variety of unactivated alkyl halides and substituted allylic carbonates to regioselectively afford E-alkenes in good to excellent yields.

KW - alkyl halides

KW - allylation

KW - allylic compounds

KW - nickel

KW - reductive coupling

UR - https://www.scopus.com/pages/publications/84855641701

U2 - 10.1002/chem.201102984

DO - 10.1002/chem.201102984

M3 - 文章

AN - SCOPUS:84855641701

SN - 0947-6539

VL - 18

SP - 808

EP - 812

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 3

ER -

Ni-catalyzed reductive allylation of unactivated alkyl halides with allylic carbonates

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this