Ni-Catalyzed cross-coupling of aryl thioethers with alkyl Grignard reagents via C-S bond cleavage

Dan Zhu; Lei Shi

doi:10.1039/c8cc03665a

Ni-Catalyzed cross-coupling of aryl thioethers with alkyl Grignard reagents via C-S bond cleavage

Dan Zhu
, Lei Shi^*

^*Corresponding author for this work

Harbin Institute of Technology Shenzhen
School of Chemistry and Chemical Engineering, Harbin Institute of Technology

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

A Ni-catalyzed cross-coupling of aryl thioethers with alkyl Grignard reagents, accompanied by the cleavage of the C(aryl)-SMe bond, has been presented. This method is distinguished by its mild conditions and moderate functional group tolerance, such as hydroxyl, halogen, and heterocycles, which should provide a straightforward access to the modification of sulfur-containing molecules.

Original language	English
Pages (from-to)	9313-9316
Number of pages	4
Journal	Chemical Communications
Volume	54
Issue number	67
DOIs	https://doi.org/10.1039/c8cc03665a
State	Published - 2018
Externally published	Yes

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title = "Ni-Catalyzed cross-coupling of aryl thioethers with alkyl Grignard reagents via C-S bond cleavage",

abstract = "A Ni-catalyzed cross-coupling of aryl thioethers with alkyl Grignard reagents, accompanied by the cleavage of the C(aryl)-SMe bond, has been presented. This method is distinguished by its mild conditions and moderate functional group tolerance, such as hydroxyl, halogen, and heterocycles, which should provide a straightforward access to the modification of sulfur-containing molecules.",

author = "Dan Zhu and Lei Shi",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/c8cc03665a",

language = "英语",

volume = "54",

pages = "9313--9316",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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T1 - Ni-Catalyzed cross-coupling of aryl thioethers with alkyl Grignard reagents via C-S bond cleavage

AU - Zhu, Dan

AU - Shi, Lei

N1 - Publisher Copyright: © The Royal Society of Chemistry.

PY - 2018

Y1 - 2018

N2 - A Ni-catalyzed cross-coupling of aryl thioethers with alkyl Grignard reagents, accompanied by the cleavage of the C(aryl)-SMe bond, has been presented. This method is distinguished by its mild conditions and moderate functional group tolerance, such as hydroxyl, halogen, and heterocycles, which should provide a straightforward access to the modification of sulfur-containing molecules.

AB - A Ni-catalyzed cross-coupling of aryl thioethers with alkyl Grignard reagents, accompanied by the cleavage of the C(aryl)-SMe bond, has been presented. This method is distinguished by its mild conditions and moderate functional group tolerance, such as hydroxyl, halogen, and heterocycles, which should provide a straightforward access to the modification of sulfur-containing molecules.

UR - https://www.scopus.com/pages/publications/85052142477

U2 - 10.1039/c8cc03665a

DO - 10.1039/c8cc03665a

M3 - 文章

C2 - 30069571

AN - SCOPUS:85052142477

SN - 1359-7345

VL - 54

SP - 9313

EP - 9316

JO - Chemical Communications

JF - Chemical Communications

IS - 67

ER -

Ni-Catalyzed cross-coupling of aryl thioethers with alkyl Grignard reagents via C-S bond cleavage

Abstract

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