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Multi-scale Label Attention Network based on Abductive Causal Graph for Disease Diagnosis

  • Haotian Wang
  • , Yi Guan*
  • , Linjiang Ma
  • , Xin Li
  • , Jing Xie
  • , Jingchi Jiang
  • *Corresponding author for this work
  • Faculty of Computing, Harbin Institute of Technology

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The auxiliary disease diagnosis based on electronic medical records is of great significance, providing doctors with diagnostic advice and avoiding misdiagnosis. Existing work on disease diagnosis mainly utilizes deep learning models to extract sequence information in electronic medical records, ignoring the interpretability of results and the structural knowledge, especially causal knowledge. In our work, we propose a multiscale label attention network based on abductive causal graph (MSLAN-ACG) to improve model accuracy and interpretability of results. First, we construct multiple encoders in the multiscale label attention network, which can extract n-gram segment information of different lengths for each disease. Meanwhile, to enhance the interpretability of results, we visualize the weight score of different segments for disease results. Second, we propose a disease representation method by defining an abductive causal graph and then using graph convolutional network for knowledge fusion on this graph. The information propagation based on abductive causal graph is consistent with the actual abductive reasoning process from symptoms to diseases, making the model more reasonable. The effectiveness of our model is demonstrated by achieving state-of-the-art results on MIMICIII-50 and ChineseEMR datasets.

Original languageEnglish
Title of host publicationProceedings - 2022 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2022
EditorsDonald Adjeroh, Qi Long, Xinghua Shi, Fei Guo, Xiaohua Hu, Srinivas Aluru, Giri Narasimhan, Jianxin Wang, Mingon Kang, Ananda M. Mondal, Jin Liu
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2542-2549
Number of pages8
ISBN (Electronic)9781665468190
DOIs
StatePublished - 2022
Externally publishedYes
Event2022 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2022 - Las Vegas, United States
Duration: 6 Dec 20228 Dec 2022

Publication series

NameProceedings - 2022 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2022

Conference

Conference2022 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2022
Country/TerritoryUnited States
CityLas Vegas
Period6/12/228/12/22

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Abductive Causal Graph
  • Disease Diagnosis
  • Label Attention
  • Multi-label Classification

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