Mixing in deformable alveolar cavity

Jun Dong; Huimin Lv; Yue Yang; Yonggang Zhu

doi:10.14264/5c5ed86

Mixing in deformable alveolar cavity

Jun Dong
, Huimin Lv
, Yue Yang
, Yonggang Zhu^*

^*Corresponding author for this work

Harbin Institute of Technology Shenzhen

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Understanding the behavior of fluid flow and micro- and nanoparticles transport in human lungs is important for studying the effect of long-term exposure to particulate contaminants and toxic aerosols on human health and the efficiency of aerosol drug delivery through lungs. The main objective of the current study is to investigate the effect of convection on species mixing in alveoli. Numerical simulations were carried out to model the periodic expansion of alveolar cavity and the species mixing in the human alveolar cavity. The mixing of species based on two different flow patterns (i.e. vortex-radial and radial flows) were studied. It is found that, for the current conditions, only vortex-radial flow can enhance the mixing in the cavity and the species transport is highly depended on the interface between fluids in the cavity and the duct. However, the mixing in the radial flow could be ignored.

Original language	English
Title of host publication	22nd Australasian Fluid Mechanics Conference, AFMC 2020
Editors	Hubert Chanson, Richard Brown
Publisher	Australasian Fluid Mechanics Society
ISBN (Electronic)	9781742723419
DOIs	https://doi.org/10.14264/5c5ed86
State	Published - 2020
Externally published	Yes
Event	22nd Australasian Fluid Mechanics Conference, AFMC 2020 - Brisbane, Australia Duration: 7 Dec 2020 → 10 Dec 2020

Publication series

Name	22nd Australasian Fluid Mechanics Conference, AFMC 2020

Conference

Conference	22nd Australasian Fluid Mechanics Conference, AFMC 2020
Country/Territory	Australia
City	Brisbane
Period	7/12/20 → 10/12/20

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Alveoli
FSI
Flow patterns
Species mixing

Access to Document

10.14264/5c5ed86

Cite this

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title = "Mixing in deformable alveolar cavity",

abstract = "Understanding the behavior of fluid flow and micro- and nanoparticles transport in human lungs is important for studying the effect of long-term exposure to particulate contaminants and toxic aerosols on human health and the efficiency of aerosol drug delivery through lungs. The main objective of the current study is to investigate the effect of convection on species mixing in alveoli. Numerical simulations were carried out to model the periodic expansion of alveolar cavity and the species mixing in the human alveolar cavity. The mixing of species based on two different flow patterns (i.e. vortex-radial and radial flows) were studied. It is found that, for the current conditions, only vortex-radial flow can enhance the mixing in the cavity and the species transport is highly depended on the interface between fluids in the cavity and the duct. However, the mixing in the radial flow could be ignored.",

keywords = "Alveoli, FSI, Flow patterns, Species mixing",

author = "Jun Dong and Huimin Lv and Yue Yang and Yonggang Zhu",

note = "Publisher Copyright: {\textcopyright} 2020 22nd Australasian Fluid Mechanics Conference, AFMC 2020. All rights reserved.; 22nd Australasian Fluid Mechanics Conference, AFMC 2020 ; Conference date: 07-12-2020 Through 10-12-2020",

year = "2020",

doi = "10.14264/5c5ed86",

language = "英语",

series = "22nd Australasian Fluid Mechanics Conference, AFMC 2020",

publisher = "Australasian Fluid Mechanics Society",

editor = "Hubert Chanson and Richard Brown",

booktitle = "22nd Australasian Fluid Mechanics Conference, AFMC 2020",

}

Dong, J, Lv, H, Yang, Y & Zhu, Y 2020, Mixing in deformable alveolar cavity. in H Chanson & R Brown (eds), 22nd Australasian Fluid Mechanics Conference, AFMC 2020. 22nd Australasian Fluid Mechanics Conference, AFMC 2020, Australasian Fluid Mechanics Society, 22nd Australasian Fluid Mechanics Conference, AFMC 2020, Brisbane, Australia, 7/12/20. https://doi.org/10.14264/5c5ed86

Mixing in deformable alveolar cavity. / Dong, Jun; Lv, Huimin; Yang, Yue et al.
22nd Australasian Fluid Mechanics Conference, AFMC 2020. ed. / Hubert Chanson; Richard Brown. Australasian Fluid Mechanics Society, 2020. (22nd Australasian Fluid Mechanics Conference, AFMC 2020).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Mixing in deformable alveolar cavity

AU - Dong, Jun

AU - Lv, Huimin

AU - Yang, Yue

AU - Zhu, Yonggang

PY - 2020

Y1 - 2020

N2 - Understanding the behavior of fluid flow and micro- and nanoparticles transport in human lungs is important for studying the effect of long-term exposure to particulate contaminants and toxic aerosols on human health and the efficiency of aerosol drug delivery through lungs. The main objective of the current study is to investigate the effect of convection on species mixing in alveoli. Numerical simulations were carried out to model the periodic expansion of alveolar cavity and the species mixing in the human alveolar cavity. The mixing of species based on two different flow patterns (i.e. vortex-radial and radial flows) were studied. It is found that, for the current conditions, only vortex-radial flow can enhance the mixing in the cavity and the species transport is highly depended on the interface between fluids in the cavity and the duct. However, the mixing in the radial flow could be ignored.

AB - Understanding the behavior of fluid flow and micro- and nanoparticles transport in human lungs is important for studying the effect of long-term exposure to particulate contaminants and toxic aerosols on human health and the efficiency of aerosol drug delivery through lungs. The main objective of the current study is to investigate the effect of convection on species mixing in alveoli. Numerical simulations were carried out to model the periodic expansion of alveolar cavity and the species mixing in the human alveolar cavity. The mixing of species based on two different flow patterns (i.e. vortex-radial and radial flows) were studied. It is found that, for the current conditions, only vortex-radial flow can enhance the mixing in the cavity and the species transport is highly depended on the interface between fluids in the cavity and the duct. However, the mixing in the radial flow could be ignored.

KW - Alveoli

KW - FSI

KW - Flow patterns

KW - Species mixing

UR - https://www.scopus.com/pages/publications/85173588441

U2 - 10.14264/5c5ed86

DO - 10.14264/5c5ed86

M3 - 会议稿件

AN - SCOPUS:85173588441

T3 - 22nd Australasian Fluid Mechanics Conference, AFMC 2020

BT - 22nd Australasian Fluid Mechanics Conference, AFMC 2020

A2 - Chanson, Hubert

A2 - Brown, Richard

PB - Australasian Fluid Mechanics Society

T2 - 22nd Australasian Fluid Mechanics Conference, AFMC 2020

Y2 - 7 December 2020 through 10 December 2020

ER -

Mixing in deformable alveolar cavity

Abstract

Publication series

Conference

UN SDGs

Keywords

Access to Document

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