Microstructure, mechanical properties, corrosion behavior and hemolysis of as-extruded biodegradable Mg-Sn-Zn alloy

L. Hou; Z. Li; Y. Pan; L. Du; X. Li; Y. Zheng; L. Li

doi:10.1063/1.4945965

Microstructure, mechanical properties, corrosion behavior and hemolysis of as-extruded biodegradable Mg-Sn-Zn alloy

L. Hou
, Z. Li^*
, Y. Pan
, L. Du
, X. Li
, Y. Zheng
, L. Li

^*Corresponding author for this work

Harbin Engineering University
Peking University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

6 Scopus citations

Abstract

As biodegradable biomaterials, magnesium alloys have favorable physical, chemical and mechanical properties, as well as good biocompatibility, and are expected to totally biodegrade in the body environment. The microstructure, mechanical properties, corrosion behaviors and hemolysis of biodegradable Mg-Sn-Zn alloy were investigated under three extrusion ratios in the present work. It is revealed that the as-extruded microstructure is obviously refined with smaller grains compared with the as-cast structure while some twins form simultaneously. The tensile strengths of the as-extruded alloys fabricated with the higher extrusion ratio is 249MPa, and elongations is 16.3% respectively. Besides, the corrosion rate of as-extruded magnesium alloys increases with the increasing extrusion ratio. The hemolysis test result shows that the hemolysis rate of biodegradable magnesium alloys fabricated with the higher extrusion ratio is 4.8%, when hemolysis rate lower than 5% has been demonstrated safe according to ISO 10993-4. In conclusion, the as-extruded biodegradable Mg-Sn-Zn alloy shows great potential as a novel medical implant material.

Original language	English
Title of host publication	International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015
Subtitle of host publication	Proceedings of the 5th International Advances in Applied Physics and Materials Science Congress and Exhibition
Editors	Seda Kol, Mehmet Emre Akoz, Zehra Banu Bahsi Oral, Ahmet Yavuz Oral, Mehmet Sezer
Publisher	American Institute of Physics Inc.
ISBN (Electronic)	9780735413740
DOIs	https://doi.org/10.1063/1.4945965
State	Published - 21 Apr 2016
Externally published	Yes
Event	5th International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015 - Oludeniz, Turkey Duration: 16 Apr 2015 → 19 Apr 2015

Publication series

Name	AIP Conference Proceedings
Volume	1727
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	5th International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015
Country/Territory	Turkey
City	Oludeniz
Period	16/04/15 → 19/04/15

Keywords

Extrusion ratio
Magnesium alloy
Properties

Access to Document

10.1063/1.4945965

Cite this

Hou, L., Li, Z., Pan, Y., Du, L., Li, X., Zheng, Y., & Li, L. (2016). Microstructure, mechanical properties, corrosion behavior and hemolysis of as-extruded biodegradable Mg-Sn-Zn alloy. In S. Kol, M. E. Akoz, Z. B. Bahsi Oral, A. Y. Oral, & M. Sezer (Eds.), International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015: Proceedings of the 5th International Advances in Applied Physics and Materials Science Congress and Exhibition Article 020010 (AIP Conference Proceedings; Vol. 1727). American Institute of Physics Inc.. https://doi.org/10.1063/1.4945965

Hou, L. ; Li, Z. ; Pan, Y. et al. / Microstructure, mechanical properties, corrosion behavior and hemolysis of as-extruded biodegradable Mg-Sn-Zn alloy. International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015: Proceedings of the 5th International Advances in Applied Physics and Materials Science Congress and Exhibition. editor / Seda Kol ; Mehmet Emre Akoz ; Zehra Banu Bahsi Oral ; Ahmet Yavuz Oral ; Mehmet Sezer. American Institute of Physics Inc., 2016. (AIP Conference Proceedings).

@inproceedings{9e3e60565a534eacb3769c7537b63e20,

title = "Microstructure, mechanical properties, corrosion behavior and hemolysis of as-extruded biodegradable Mg-Sn-Zn alloy",

abstract = "As biodegradable biomaterials, magnesium alloys have favorable physical, chemical and mechanical properties, as well as good biocompatibility, and are expected to totally biodegrade in the body environment. The microstructure, mechanical properties, corrosion behaviors and hemolysis of biodegradable Mg-Sn-Zn alloy were investigated under three extrusion ratios in the present work. It is revealed that the as-extruded microstructure is obviously refined with smaller grains compared with the as-cast structure while some twins form simultaneously. The tensile strengths of the as-extruded alloys fabricated with the higher extrusion ratio is 249MPa, and elongations is 16.3\% respectively. Besides, the corrosion rate of as-extruded magnesium alloys increases with the increasing extrusion ratio. The hemolysis test result shows that the hemolysis rate of biodegradable magnesium alloys fabricated with the higher extrusion ratio is 4.8\%, when hemolysis rate lower than 5\% has been demonstrated safe according to ISO 10993-4. In conclusion, the as-extruded biodegradable Mg-Sn-Zn alloy shows great potential as a novel medical implant material.",

keywords = "Extrusion ratio, Magnesium alloy, Properties",

author = "L. Hou and Z. Li and Y. Pan and L. Du and X. Li and Y. Zheng and L. Li",

note = "Publisher Copyright: {\textcopyright} 2016 Author(s).; 5th International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015 ; Conference date: 16-04-2015 Through 19-04-2015",

year = "2016",

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doi = "10.1063/1.4945965",

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series = "AIP Conference Proceedings",

publisher = "American Institute of Physics Inc.",

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Hou, L, Li, Z, Pan, Y, Du, L, Li, X, Zheng, Y & Li, L 2016, Microstructure, mechanical properties, corrosion behavior and hemolysis of as-extruded biodegradable Mg-Sn-Zn alloy. in S Kol, ME Akoz, ZB Bahsi Oral, AY Oral & M Sezer (eds), International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015: Proceedings of the 5th International Advances in Applied Physics and Materials Science Congress and Exhibition., 020010, AIP Conference Proceedings, vol. 1727, American Institute of Physics Inc., 5th International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015, Oludeniz, Turkey, 16/04/15. https://doi.org/10.1063/1.4945965

Microstructure, mechanical properties, corrosion behavior and hemolysis of as-extruded biodegradable Mg-Sn-Zn alloy. / Hou, L.; Li, Z.; Pan, Y. et al.
International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015: Proceedings of the 5th International Advances in Applied Physics and Materials Science Congress and Exhibition. ed. / Seda Kol; Mehmet Emre Akoz; Zehra Banu Bahsi Oral; Ahmet Yavuz Oral; Mehmet Sezer. American Institute of Physics Inc., 2016. 020010 (AIP Conference Proceedings; Vol. 1727).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Microstructure, mechanical properties, corrosion behavior and hemolysis of as-extruded biodegradable Mg-Sn-Zn alloy

AU - Hou, L.

AU - Li, Z.

AU - Pan, Y.

AU - Du, L.

AU - Li, X.

AU - Zheng, Y.

AU - Li, L.

PY - 2016/4/21

Y1 - 2016/4/21

N2 - As biodegradable biomaterials, magnesium alloys have favorable physical, chemical and mechanical properties, as well as good biocompatibility, and are expected to totally biodegrade in the body environment. The microstructure, mechanical properties, corrosion behaviors and hemolysis of biodegradable Mg-Sn-Zn alloy were investigated under three extrusion ratios in the present work. It is revealed that the as-extruded microstructure is obviously refined with smaller grains compared with the as-cast structure while some twins form simultaneously. The tensile strengths of the as-extruded alloys fabricated with the higher extrusion ratio is 249MPa, and elongations is 16.3% respectively. Besides, the corrosion rate of as-extruded magnesium alloys increases with the increasing extrusion ratio. The hemolysis test result shows that the hemolysis rate of biodegradable magnesium alloys fabricated with the higher extrusion ratio is 4.8%, when hemolysis rate lower than 5% has been demonstrated safe according to ISO 10993-4. In conclusion, the as-extruded biodegradable Mg-Sn-Zn alloy shows great potential as a novel medical implant material.

AB - As biodegradable biomaterials, magnesium alloys have favorable physical, chemical and mechanical properties, as well as good biocompatibility, and are expected to totally biodegrade in the body environment. The microstructure, mechanical properties, corrosion behaviors and hemolysis of biodegradable Mg-Sn-Zn alloy were investigated under three extrusion ratios in the present work. It is revealed that the as-extruded microstructure is obviously refined with smaller grains compared with the as-cast structure while some twins form simultaneously. The tensile strengths of the as-extruded alloys fabricated with the higher extrusion ratio is 249MPa, and elongations is 16.3% respectively. Besides, the corrosion rate of as-extruded magnesium alloys increases with the increasing extrusion ratio. The hemolysis test result shows that the hemolysis rate of biodegradable magnesium alloys fabricated with the higher extrusion ratio is 4.8%, when hemolysis rate lower than 5% has been demonstrated safe according to ISO 10993-4. In conclusion, the as-extruded biodegradable Mg-Sn-Zn alloy shows great potential as a novel medical implant material.

KW - Extrusion ratio

KW - Magnesium alloy

KW - Properties

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U2 - 10.1063/1.4945965

DO - 10.1063/1.4945965

M3 - 会议稿件

AN - SCOPUS:84984571748

T3 - AIP Conference Proceedings

BT - International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015

A2 - Kol, Seda

A2 - Akoz, Mehmet Emre

A2 - Bahsi Oral, Zehra Banu

A2 - Oral, Ahmet Yavuz

A2 - Sezer, Mehmet

PB - American Institute of Physics Inc.

T2 - 5th International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015

Y2 - 16 April 2015 through 19 April 2015

ER -

Hou L, Li Z, Pan Y, Du L, Li X, Zheng Y et al. Microstructure, mechanical properties, corrosion behavior and hemolysis of as-extruded biodegradable Mg-Sn-Zn alloy. In Kol S, Akoz ME, Bahsi Oral ZB, Oral AY, Sezer M, editors, International Advances in Applied Physics and Materials Science Congress and Exhibition, APMAS 2015: Proceedings of the 5th International Advances in Applied Physics and Materials Science Congress and Exhibition. American Institute of Physics Inc. 2016. 020010. (AIP Conference Proceedings). doi: 10.1063/1.4945965

Microstructure, mechanical properties, corrosion behavior and hemolysis of as-extruded biodegradable Mg-Sn-Zn alloy

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