Mathematical modeling and simulation study of the heart rate feedback regulation system

Xiaoping Shi; Yuyun Zhu

Mathematical modeling and simulation study of the heart rate feedback regulation system

Xiaoping Shi^*
, Yuyun Zhu

^*Corresponding author for this work

School of Astronautics

Harbin Institute of Technology

Research output: Contribution to journal › Article › peer-review

Abstract

The physiological feedback regulation mechanism of the heart rate variation due to the blood pressure variation is studied. The continuous closed-loop mathematical model of the heart rate feedback regulation system is constructed. Numerical simulation is completed based on the above model. The simulation results demonstrate that the regulation system has the ability to constrain the fluctuation of the blood pressure to certain extent. The results are helpful for the pathological studies of some hypertensive diseases.

Original language	English
Pages (from-to)	926-929
Number of pages	4
Journal	Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering
Volume	21
Issue number	6
State	Published - Dec 2004

Cite this

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title = "Mathematical modeling and simulation study of the heart rate feedback regulation system",

abstract = "The physiological feedback regulation mechanism of the heart rate variation due to the blood pressure variation is studied. The continuous closed-loop mathematical model of the heart rate feedback regulation system is constructed. Numerical simulation is completed based on the above model. The simulation results demonstrate that the regulation system has the ability to constrain the fluctuation of the blood pressure to certain extent. The results are helpful for the pathological studies of some hypertensive diseases.",

author = "Xiaoping Shi and Yuyun Zhu",

year = "2004",

month = dec,

language = "英语",

volume = "21",

pages = "926--929",

journal = "Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering",

issn = "1001-5515",

publisher = "West China Hospital, Sichuan Institute of Biomedical Engineering",

number = "6",

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AU - Shi, Xiaoping

AU - Zhu, Yuyun

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AB - The physiological feedback regulation mechanism of the heart rate variation due to the blood pressure variation is studied. The continuous closed-loop mathematical model of the heart rate feedback regulation system is constructed. Numerical simulation is completed based on the above model. The simulation results demonstrate that the regulation system has the ability to constrain the fluctuation of the blood pressure to certain extent. The results are helpful for the pathological studies of some hypertensive diseases.

UR - https://www.scopus.com/pages/publications/33644691669

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SN - 1001-5515

VL - 21

SP - 926

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JO - Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering

JF - Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering

IS - 6

ER -

Mathematical modeling and simulation study of the heart rate feedback regulation system

Abstract

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