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Limiting search space in bayesian network using GGM

  • Qing Zhang*
  • , Samuel S.M. Sun
  • , Yong Cao
  • , Dianjing Guo
  • *Corresponding author for this work
  • Chinese University of Hong Kong
  • Harbin Institute of Technology Shenzhen

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this paper, we describe a modified greedy search method for selecting the highest Bayesian score. Particularly, our method uses GGM to limit the searching space based on the partial correlation value. We demonstrate that our method achieved comparable results with classical method and saved ~50% of computational time. The modified greedy search method can be widely used for efficient network inference in systems biology.

Original languageEnglish
Title of host publicationICBBT 2010 - 2010 International Conference on Bioinformatics and Biomedical Technology
Pages283-287
Number of pages5
DOIs
StatePublished - 2010
Externally publishedYes
Event2010 International Conference on Bioinformatics and Biomedical Technology, ICBBT 2010 - Chengdu, China
Duration: 16 Apr 201018 Apr 2010

Publication series

NameICBBT 2010 - 2010 International Conference on Bioinformatics and Biomedical Technology

Conference

Conference2010 International Conference on Bioinformatics and Biomedical Technology, ICBBT 2010
Country/TerritoryChina
CityChengdu
Period16/04/1018/04/10

Keywords

  • Bayesian network
  • Graphicalg aussian model
  • Greedy search
  • Partial correlation
  • Systems biology

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