Ligand-promoted C-3 selective C-H olefination of pyridines with Pd catalysts

Mengchun Ye; Guo Lin Gao; Jin Quan Yu

doi:10.1021/ja2021075

Ligand-promoted C-3 selective C-H olefination of pyridines with Pd catalysts

Mengchun Ye
, Guo Lin Gao
, Jin Quan Yu^*

^*Corresponding author for this work

Scripps Research Institute

Research output: Contribution to journal › Article › peer-review

341 Scopus citations

Abstract

Pd-catalyzed C-3 selective olefination of pyridines is developed for the first time using 1,10-phenanthroline as the ligand. This finding provides a novel disconnection for the synthesis of pyridine-containing alkaloids and drug molecules as well as a new approach for developing Pd-catalyzed C-H functionalizations of pyridines.

Original language	English
Pages (from-to)	6964-6967
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	133
Issue number	18
DOIs	https://doi.org/10.1021/ja2021075
State	Published - 11 May 2011
Externally published	Yes

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10.1021/ja2021075

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title = "Ligand-promoted C-3 selective C-H olefination of pyridines with Pd catalysts",

abstract = "Pd-catalyzed C-3 selective olefination of pyridines is developed for the first time using 1,10-phenanthroline as the ligand. This finding provides a novel disconnection for the synthesis of pyridine-containing alkaloids and drug molecules as well as a new approach for developing Pd-catalyzed C-H functionalizations of pyridines.",

author = "Mengchun Ye and Gao, \{Guo Lin\} and Yu, \{Jin Quan\}",

year = "2011",

month = may,

day = "11",

doi = "10.1021/ja2021075",

language = "英语",

volume = "133",

pages = "6964--6967",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

number = "18",

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T1 - Ligand-promoted C-3 selective C-H olefination of pyridines with Pd catalysts

AU - Ye, Mengchun

AU - Gao, Guo Lin

AU - Yu, Jin Quan

PY - 2011/5/11

Y1 - 2011/5/11

N2 - Pd-catalyzed C-3 selective olefination of pyridines is developed for the first time using 1,10-phenanthroline as the ligand. This finding provides a novel disconnection for the synthesis of pyridine-containing alkaloids and drug molecules as well as a new approach for developing Pd-catalyzed C-H functionalizations of pyridines.

AB - Pd-catalyzed C-3 selective olefination of pyridines is developed for the first time using 1,10-phenanthroline as the ligand. This finding provides a novel disconnection for the synthesis of pyridine-containing alkaloids and drug molecules as well as a new approach for developing Pd-catalyzed C-H functionalizations of pyridines.

UR - https://www.scopus.com/pages/publications/79955684836

U2 - 10.1021/ja2021075

DO - 10.1021/ja2021075

M3 - 文章

C2 - 21491938

AN - SCOPUS:79955684836

SN - 0002-7863

VL - 133

SP - 6964

EP - 6967

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 18

ER -

Ligand-promoted C-3 selective C-H olefination of pyridines with Pd catalysts

Abstract

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