Label-free monitoring of molecular binding based on extraordinary optical transmission with enhanced accuracy

Long Tu; Liang Huang; Shouhong Jin; Xuzhou Li; Lu Mi; Qiong Wu; Wenhui Wang

doi:10.1109/MEMSYS.2016.7421622

Label-free monitoring of molecular binding based on extraordinary optical transmission with enhanced accuracy

Long Tu
, Liang Huang
, Shouhong Jin
, Xuzhou Li
, Lu Mi
, Qiong Wu
, Wenhui Wang^*

^*Corresponding author for this work

Tsinghua University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

This paper describes a preliminary study of the anti-HIV antibody 10E8 and Membrane Proximal External Re Gion (MPER) antigen's interaction based on extraordinary optical transmission (EOT) enabled by a free-standing gold film perforated with periodically arrayed nano-holes. Particularly, the spectral shift caused by the microfluidic flow rate through the porous and suspended Au/Cr/Si3N4 film has been quantified for the first time and this shift as measurement error has been decoupled and eliminated from the recorded signal to enhance the monitoring accuracy.

Original language	English
Title of host publication	MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	311-314
Number of pages	4
ISBN (Electronic)	9781509019731
DOIs	https://doi.org/10.1109/MEMSYS.2016.7421622
State	Published - 26 Feb 2016
Externally published	Yes
Event	29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016 - Shanghai, China Duration: 24 Jan 2016 → 28 Jan 2016

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume	2016-February
ISSN (Print)	1084-6999

Conference

Conference	29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016
Country/Territory	China
City	Shanghai
Period	24/01/16 → 28/01/16

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1109/MEMSYS.2016.7421622

Cite this

Tu, L., Huang, L., Jin, S., Li, X., Mi, L., Wu, Q., & Wang, W. (2016). Label-free monitoring of molecular binding based on extraordinary optical transmission with enhanced accuracy. In MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems (pp. 311-314). Article 7421622 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); Vol. 2016-February). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMSYS.2016.7421622

Tu, Long ; Huang, Liang ; Jin, Shouhong et al. / Label-free monitoring of molecular binding based on extraordinary optical transmission with enhanced accuracy. MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems. Institute of Electrical and Electronics Engineers Inc., 2016. pp. 311-314 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

@inproceedings{5aa7c1569c4448f4b06e158d02904ebf,

title = "Label-free monitoring of molecular binding based on extraordinary optical transmission with enhanced accuracy",

abstract = "This paper describes a preliminary study of the anti-HIV antibody 10E8 and Membrane Proximal External Re Gion (MPER) antigen's interaction based on extraordinary optical transmission (EOT) enabled by a free-standing gold film perforated with periodically arrayed nano-holes. Particularly, the spectral shift caused by the microfluidic flow rate through the porous and suspended Au/Cr/Si3N4 film has been quantified for the first time and this shift as measurement error has been decoupled and eliminated from the recorded signal to enhance the monitoring accuracy.",

author = "Long Tu and Liang Huang and Shouhong Jin and Xuzhou Li and Lu Mi and Qiong Wu and Wenhui Wang",

note = "Publisher Copyright: {\textcopyright} 2016 IEEE.; 29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016 ; Conference date: 24-01-2016 Through 28-01-2016",

year = "2016",

month = feb,

day = "26",

doi = "10.1109/MEMSYS.2016.7421622",

language = "英语",

series = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "311--314",

booktitle = "MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems",

address = "美国",

}

Tu, L, Huang, L, Jin, S, Li, X, Mi, L, Wu, Q & Wang, W 2016, Label-free monitoring of molecular binding based on extraordinary optical transmission with enhanced accuracy. in MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems., 7421622, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), vol. 2016-February, Institute of Electrical and Electronics Engineers Inc., pp. 311-314, 29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016, Shanghai, China, 24/01/16. https://doi.org/10.1109/MEMSYS.2016.7421622

Label-free monitoring of molecular binding based on extraordinary optical transmission with enhanced accuracy. / Tu, Long; Huang, Liang; Jin, Shouhong et al.
MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems. Institute of Electrical and Electronics Engineers Inc., 2016. p. 311-314 7421622 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); Vol. 2016-February).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - Label-free monitoring of molecular binding based on extraordinary optical transmission with enhanced accuracy

AU - Tu, Long

AU - Huang, Liang

AU - Jin, Shouhong

AU - Li, Xuzhou

AU - Mi, Lu

AU - Wu, Qiong

AU - Wang, Wenhui

PY - 2016/2/26

Y1 - 2016/2/26

N2 - This paper describes a preliminary study of the anti-HIV antibody 10E8 and Membrane Proximal External Re Gion (MPER) antigen's interaction based on extraordinary optical transmission (EOT) enabled by a free-standing gold film perforated with periodically arrayed nano-holes. Particularly, the spectral shift caused by the microfluidic flow rate through the porous and suspended Au/Cr/Si3N4 film has been quantified for the first time and this shift as measurement error has been decoupled and eliminated from the recorded signal to enhance the monitoring accuracy.

AB - This paper describes a preliminary study of the anti-HIV antibody 10E8 and Membrane Proximal External Re Gion (MPER) antigen's interaction based on extraordinary optical transmission (EOT) enabled by a free-standing gold film perforated with periodically arrayed nano-holes. Particularly, the spectral shift caused by the microfluidic flow rate through the porous and suspended Au/Cr/Si3N4 film has been quantified for the first time and this shift as measurement error has been decoupled and eliminated from the recorded signal to enhance the monitoring accuracy.

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U2 - 10.1109/MEMSYS.2016.7421622

DO - 10.1109/MEMSYS.2016.7421622

M3 - 会议稿件

AN - SCOPUS:84970968840

T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

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EP - 314

BT - MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016

Y2 - 24 January 2016 through 28 January 2016

ER -

Tu L, Huang L, Jin S, Li X, Mi L, Wu Q et al. Label-free monitoring of molecular binding based on extraordinary optical transmission with enhanced accuracy. In MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems. Institute of Electrical and Electronics Engineers Inc. 2016. p. 311-314. 7421622. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). doi: 10.1109/MEMSYS.2016.7421622

Label-free monitoring of molecular binding based on extraordinary optical transmission with enhanced accuracy

Abstract

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