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Interaction of pH-responsive polyanions with phospholipid membranes

  • Edit Brodszkij
  • , Martin J. Hviid
  • , Carina Ade
  • , Philipp S. Schattling
  • , Moritz Burmeister
  • , Sven Szilagyi
  • , Noga Gal
  • , Chuntao Zhu
  • , Xiaojun Han
  • , Brigitte Städler*
  • *Corresponding author for this work
  • Aarhus University
  • School of Chemistry and Chemical Engineering, Harbin Institute of Technology

Research output: Contribution to journalArticlepeer-review

Abstract

The behavior of two acrylate polymers, with carboxylic acid side groups, was investigated with regard to their pH-responsive interaction with phospholipid membranes. The polyanions crossed the membrane of giant unilamellar vesicles and mammalian cells with low cytotoxicity in the latter case.

Original languageEnglish
Pages (from-to)5992-5997
Number of pages6
JournalPolymer Chemistry
Volume10
Issue number44
DOIs
StatePublished - 28 Nov 2019
Externally publishedYes

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