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Influence of Picosecond Laser Process Parameters on the Ablation of Vitro Skin Tissue

  • Zhan Jinming
  • , Wu Xuefeng*
  • , Yang Lijun
  • , Ding Ye
  • , Liu Weiting
  • *Corresponding author for this work
  • Harbin University of Science and Technology

Research output: Contribution to journalArticlepeer-review

Abstract

Given the demand for ablation treatment using picosecond lasers in medical cosmetology, researchers analyze the degree of thermal damage to skin tissue by combining theoretical modeling with experimental research. The effects of laser scanning speed, number of scans (30–90) and scanning paths on the heat-affected zone, ablation depth, and thermal damage were investigated using one-way analysis of variance. The results show that increasing the scanning speed can reduce the heat-affected zone; the number of repeated scans is positively correlated with the ablation depth; and the concentric circle scanning path can reduce the accumulation of thermal damage compared with linear scanning. On this basis, the optimal combination of process parameters is obtained, with good macroscopic morphology and lower thermal damage than continuous lasers.

Original languageEnglish
Article numbere202500174
JournalJournal of Biophotonics
Volume18
Issue number11
DOIs
StatePublished - Nov 2025

Keywords

  • picosecond laser
  • process optimization
  • scanning path
  • skin tissue ablation
  • thermal damage

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