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imDC: An ensemble learning method for imbalanced classification with miRNA data

  • C. Y. Wang*
  • , M. Z. Guo
  • , X. Y. Liu
  • *Corresponding author for this work
  • School of Computer Science and Technology, Harbin Institute of Technology
  • Xiamen University

Research output: Contribution to journalArticlepeer-review

Abstract

Imbalances typically exist in bioinformatics and are also common in other areas. A drawback of traditional machine learning methods is the relatively little attention given to small sample classification. Thus, we developed imDC, which uses an ensemble learning concept in combination with weights and sample misclassification information to effectively classify imbalanced data. Our method showed better results when compared to other algorithms with UCI machine learning datasets and microRNA data.

Original languageEnglish
Pages (from-to)123-133
Number of pages11
JournalGenetics and Molecular Research
Volume14
Issue number1
DOIs
StatePublished - 15 Jan 2015
Externally publishedYes

Keywords

  • Bioinformatics
  • Ensemble learning
  • Imbalances
  • Machine learning
  • miRNA

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