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Hydrodynamically driven self-assembly of giant vesicles of metal nanoparticles for remote-controlled release

  • Jie He*
  • , Zengjiang Wei
  • , Lei Wang
  • , Zuleykhan Tomova
  • , Taarika Babu
  • , Chaoyang Wang
  • , Xiaojun Han
  • , John T. Fourkas
  • , Zhihong Nie
  • *Corresponding author for this work
  • University of Maryland, College Park
  • South China University of Technology
  • School of Chemistry and Chemical Engineering, Harbin Institute of Technology

Research output: Contribution to journalArticlepeer-review

Abstract

The hydrodynamics of laminar flow in a microfluidic device has been used to control the continuous self-assembly of gold nanoparticles (NPs) tethered with amphiphilic block copolymers. Spherical micelles, giant vesicles (500 nm-2.0 μm), or disk-like micelles could be formed by varying the flow rates of fluids. Such vesicles can release encapsulated hydrophilic species by using near-IR light (see picture).

Original languageEnglish
Pages (from-to)2463-2468
Number of pages6
JournalAngewandte Chemie - International Edition
Volume52
Issue number9
DOIs
StatePublished - 25 Feb 2013
Externally publishedYes

Keywords

  • giant vesicles
  • nanoparticles
  • photothermal effect
  • plasmonic properties
  • self-assembly

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