Growth of hydroxyapatite coating on polymer microspheres

Zhang Zhe; Sam Zhang; Subbu S. Venkatraman; Shang Lei

doi:10.1166/nnl.2011.1204

Growth of hydroxyapatite coating on polymer microspheres

Zhang Zhe
, Sam Zhang^*
, Subbu S. Venkatraman
, Shang Lei

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Hydroxyapatite (HA) coated polymer microspheres was prepared by a two-step process under physiological temperature and pH value. A full coverage of plate-like structured HA coating was achieved on poly(lactic-co-glycolic acid) (PLGA) microspheres. Field emission scanning electron microscopy was employed to observe the surface morphology of microspheres before and after coating. Fourier Transform Infrared spectra and X-ray diffraction were used for the chemical groups and crystal structure examination. The HA coated PLGA microspheres have potential applications in controlled drug delivery systems.

Original language	English
Pages (from-to)	472-476
Number of pages	5
Journal	Nanoscience and Nanotechnology Letters
Volume	3
Issue number	4
DOIs	https://doi.org/10.1166/nnl.2011.1204
State	Published - Aug 2011
Externally published	Yes

Keywords

Biomimetic
Drug delivery
Hydroxyapatite coating
Poly(lactic-co-glycolic acid) microspheres

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10.1166/nnl.2011.1204

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title = "Growth of hydroxyapatite coating on polymer microspheres",

abstract = "Hydroxyapatite (HA) coated polymer microspheres was prepared by a two-step process under physiological temperature and pH value. A full coverage of plate-like structured HA coating was achieved on poly(lactic-co-glycolic acid) (PLGA) microspheres. Field emission scanning electron microscopy was employed to observe the surface morphology of microspheres before and after coating. Fourier Transform Infrared spectra and X-ray diffraction were used for the chemical groups and crystal structure examination. The HA coated PLGA microspheres have potential applications in controlled drug delivery systems.",

keywords = "Biomimetic, Drug delivery, Hydroxyapatite coating, Poly(lactic-co-glycolic acid) microspheres",

author = "Zhang Zhe and Sam Zhang and Venkatraman, \{Subbu S.\} and Shang Lei",

year = "2011",

month = aug,

doi = "10.1166/nnl.2011.1204",

language = "英语",

volume = "3",

pages = "472--476",

journal = "Nanoscience and Nanotechnology Letters",

issn = "1941-4900",

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TY - JOUR

T1 - Growth of hydroxyapatite coating on polymer microspheres

AU - Zhe, Zhang

AU - Zhang, Sam

AU - Venkatraman, Subbu S.

AU - Lei, Shang

PY - 2011/8

Y1 - 2011/8

N2 - Hydroxyapatite (HA) coated polymer microspheres was prepared by a two-step process under physiological temperature and pH value. A full coverage of plate-like structured HA coating was achieved on poly(lactic-co-glycolic acid) (PLGA) microspheres. Field emission scanning electron microscopy was employed to observe the surface morphology of microspheres before and after coating. Fourier Transform Infrared spectra and X-ray diffraction were used for the chemical groups and crystal structure examination. The HA coated PLGA microspheres have potential applications in controlled drug delivery systems.

AB - Hydroxyapatite (HA) coated polymer microspheres was prepared by a two-step process under physiological temperature and pH value. A full coverage of plate-like structured HA coating was achieved on poly(lactic-co-glycolic acid) (PLGA) microspheres. Field emission scanning electron microscopy was employed to observe the surface morphology of microspheres before and after coating. Fourier Transform Infrared spectra and X-ray diffraction were used for the chemical groups and crystal structure examination. The HA coated PLGA microspheres have potential applications in controlled drug delivery systems.

KW - Biomimetic

KW - Drug delivery

KW - Hydroxyapatite coating

KW - Poly(lactic-co-glycolic acid) microspheres

UR - https://www.scopus.com/pages/publications/80053949943

U2 - 10.1166/nnl.2011.1204

DO - 10.1166/nnl.2011.1204

M3 - 文章

AN - SCOPUS:80053949943

SN - 1941-4900

VL - 3

SP - 472

EP - 476

JO - Nanoscience and Nanotechnology Letters

JF - Nanoscience and Nanotechnology Letters

IS - 4

ER -

Growth of hydroxyapatite coating on polymer microspheres

Abstract

Keywords

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