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Forecastable and Guidable Bubble-Propelled Microplate Motors for Cell Transport

  • Narisu Hu
  • , Bin Zhang
  • , Meiyu Gai
  • , Ce Zheng
  • , Johannes Frueh*
  • , Qiang He
  • *Corresponding author for this work
  • Harbin Institute of Technology
  • The Second Affiliated Hospital of Harbin Medical University
  • Queen Mary University of London
  • Harbin Medical University

Research output: Contribution to journalArticlepeer-review

Abstract

Cell transport is important to renew body functions and organs with stem cells, or to attack cancer cells with immune cells. The main hindrances of this method are the lack of understanding of cell motion as well as proper transport systems. In this publication, bubble-propelled polyelectrolyte microplates are used for controlled transport and guidance of HeLa cells. Cells survive attachment on the microplates and up to 22 min in 5% hydrogen peroxide solution. They can be guided by a magnetic field whereby increased friction of cells attached to microplates decreases the speed by 90% compared to pristine microplates. The motion direction of the cell–motor system is easier to predict due to the cell being opposite to the bubbles. (Figure presented.).

Original languageEnglish
Article number1600795
JournalMacromolecular Rapid Communications
Volume38
Issue number11
DOIs
StatePublished - Jun 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • bubble propulsion
  • cell transport
  • motion analysis
  • motion control
  • plate micromotor

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