@inproceedings{398b74892925450383d29d445714f8a2,
title = "Enhancing the sensing performance of aptameric gfets for interleukin-6 detection using negative electric field",
abstract = "We propose an approach which can enhance the functionalization density of 1-pyrenebutanoic acid succinimidyl ester (PASE) as well as its linked aptamer by applying negative electric field during PASE functionalization. Due to the electrostatic repulsion, polar molecule PASE is arranged regularly with directivity with the electron-rich pyrenyl group forced towards graphene, thus possibly making further quantities of PASE interact with graphene. Experimental results indicate that the detection limit (DL) of aptameric GFETs for detecting interleukon-6 (IL-6) decreased from 1.47 to 0.83 pM after applying a voltage of -0.3V for 3h during PASE functionalization.",
keywords = "Aptamer, GFET, Interleukon-6 (IL-6), Negative electric field, Sensing performance enhancement",
author = "Zhuang Hao and Yunlu Pan and Cong Huang and Xuezeng Zhao",
note = "Publisher Copyright: {\textcopyright} 2019 CBMS-0001.; 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 ; Conference date: 27-10-2019 Through 31-10-2019",
year = "2019",
language = "英语",
series = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",
publisher = "Chemical and Biological Microsystems Society",
pages = "1236--1237",
booktitle = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",
}