Enhancing electrochemical detection of dopamine: Via dumbbell-like FePt-Fe3O4 nanoparticles

Weiwei Yang; Yongsheng Yu; Ying Tang; Keyun Li; Zheng Zhao; Menggang Li; Geping Yin; Haibo Li; Shouheng Sun

doi:10.1039/c6nr08507e

Enhancing electrochemical detection of dopamine: Via dumbbell-like FePt-Fe₃O₄ nanoparticles

Weiwei Yang
, Yongsheng Yu^*
, Ying Tang
, Keyun Li
, Zheng Zhao
, Menggang Li
, Geping Yin
, Haibo Li
, Shouheng Sun

^*Corresponding author for this work

School of Chemistry and Chemical Engineering, Harbin Institute of Technology
The First Affiliated Hospital of Harbin Medical University
Jilin Normal University
Brown University

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

We synthesize dumbbell-like FePt-Fe₃O₄ nanoparticles (NPs) and study their electrocatalytic oxidation and sensing of dopamine (DA). The FePt and Fe₃O₄ NPs are strongly coupled in the dumbbell structure and as a result, the dumbbell FePt-Fe₃O₄ NPs show the best activity for DA oxidation with the DA detection limit reaching 1 nM. They are used successfully to monitor the DA concentration increase induced by K⁺-stimulation of PC12 cells. Our data show that an electrode modified with dumbbell-like FePt-Fe₃O₄ NPs can serve as the most sensitive probe for real-time quantitative detection of DA in a neurological environment.

Original language	English
Pages (from-to)	1022-1027
Number of pages	6
Journal	Nanoscale
Volume	9
Issue number	3
DOIs	https://doi.org/10.1039/c6nr08507e
State	Published - 21 Jan 2017
Externally published	Yes

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title = "Enhancing electrochemical detection of dopamine: Via dumbbell-like FePt-Fe3O4 nanoparticles",

abstract = "We synthesize dumbbell-like FePt-Fe3O4 nanoparticles (NPs) and study their electrocatalytic oxidation and sensing of dopamine (DA). The FePt and Fe3O4 NPs are strongly coupled in the dumbbell structure and as a result, the dumbbell FePt-Fe3O4 NPs show the best activity for DA oxidation with the DA detection limit reaching 1 nM. They are used successfully to monitor the DA concentration increase induced by K+-stimulation of PC12 cells. Our data show that an electrode modified with dumbbell-like FePt-Fe3O4 NPs can serve as the most sensitive probe for real-time quantitative detection of DA in a neurological environment.",

author = "Weiwei Yang and Yongsheng Yu and Ying Tang and Keyun Li and Zheng Zhao and Menggang Li and Geping Yin and Haibo Li and Shouheng Sun",

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TY - JOUR

T1 - Enhancing electrochemical detection of dopamine

T2 - Via dumbbell-like FePt-Fe3O4 nanoparticles

AU - Yang, Weiwei

AU - Yu, Yongsheng

AU - Tang, Ying

AU - Li, Keyun

AU - Zhao, Zheng

AU - Li, Menggang

AU - Yin, Geping

AU - Li, Haibo

AU - Sun, Shouheng

PY - 2017/1/21

Y1 - 2017/1/21

N2 - We synthesize dumbbell-like FePt-Fe3O4 nanoparticles (NPs) and study their electrocatalytic oxidation and sensing of dopamine (DA). The FePt and Fe3O4 NPs are strongly coupled in the dumbbell structure and as a result, the dumbbell FePt-Fe3O4 NPs show the best activity for DA oxidation with the DA detection limit reaching 1 nM. They are used successfully to monitor the DA concentration increase induced by K+-stimulation of PC12 cells. Our data show that an electrode modified with dumbbell-like FePt-Fe3O4 NPs can serve as the most sensitive probe for real-time quantitative detection of DA in a neurological environment.

AB - We synthesize dumbbell-like FePt-Fe3O4 nanoparticles (NPs) and study their electrocatalytic oxidation and sensing of dopamine (DA). The FePt and Fe3O4 NPs are strongly coupled in the dumbbell structure and as a result, the dumbbell FePt-Fe3O4 NPs show the best activity for DA oxidation with the DA detection limit reaching 1 nM. They are used successfully to monitor the DA concentration increase induced by K+-stimulation of PC12 cells. Our data show that an electrode modified with dumbbell-like FePt-Fe3O4 NPs can serve as the most sensitive probe for real-time quantitative detection of DA in a neurological environment.

UR - https://www.scopus.com/pages/publications/85010280597

U2 - 10.1039/c6nr08507e

DO - 10.1039/c6nr08507e

M3 - 文章

C2 - 28045168

AN - SCOPUS:85010280597

SN - 2040-3364

VL - 9

SP - 1022

EP - 1027

JO - Nanoscale

JF - Nanoscale

IS - 3

ER -

Enhancing electrochemical detection of dopamine: Via dumbbell-like FePt-Fe₃O₄ nanoparticles

Abstract

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