Electrochemical corrosion and bioactivity of Ti-Nb-Sn-hydroxyapatite composites fabricated by pulse current activated sintering

Wang Xiaopeng; Kong Fantao; Han Biqing; Chen Yuyong

doi:10.1016/j.jmbbm.2017.07.025

Electrochemical corrosion and bioactivity of Ti-Nb-Sn-hydroxyapatite composites fabricated by pulse current activated sintering

Wang Xiaopeng^*
, Kong Fantao
, Han Biqing
, Chen Yuyong

^*Corresponding author for this work

School of Materials Science and Engineering

Harbin Institute of Technology
The Second Affiliated Hospital of Harbin Medical University

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Ti-Nb-Sn-hydroxyapatite (HA) composites were prepared by mechanical alloying for different times (unmilled, 4, 8 and 12 h), followed by pulse current activated sintering. The effects of the milling time on the electrochemical corrosion resistance and bioactivity of the sintered Ti-35Nb-2.5Sn-15HA composites were investigated. Potentiodynamic polarization test results indicated that the sintered Ti-35Nb-2.5Sn-15HA composites exhibited higher corrosion resistance with increasing milling time. The corrosion potential and current of the Ti-35Nb-2.5Sn-15HA composite sintered by 12 h milled powders were − 0.261 V and 0.18 μA/cm², respectively, and this sintered composite showed a stable and wide passivation region. The hemolysis rate of the sintered Ti-35Nb-2.5Sn-15HA composites reduced with increasing milling time and the lowest hemolytic rate of the composites was 0.87%. In addition, the in vitro cell culture results indicated that the composite sintered by 12 h milled powders had good biocompatibility. These results indicate the significant potential of Ti-35Nb-2.5Sn/xHA composites for biomedical implant applications.

Original language	English
Pages (from-to)	222-227
Number of pages	6
Journal	Journal of the Mechanical Behavior of Biomedical Materials
Volume	75
DOIs	https://doi.org/10.1016/j.jmbbm.2017.07.025
State	Published - Nov 2017

Keywords

Bioactivity
Electrochemical corrosion
Milling time
Ti-Nb-Sn/HA composites

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10.1016/j.jmbbm.2017.07.025

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title = "Electrochemical corrosion and bioactivity of Ti-Nb-Sn-hydroxyapatite composites fabricated by pulse current activated sintering",

abstract = "Ti-Nb-Sn-hydroxyapatite (HA) composites were prepared by mechanical alloying for different times (unmilled, 4, 8 and 12 h), followed by pulse current activated sintering. The effects of the milling time on the electrochemical corrosion resistance and bioactivity of the sintered Ti-35Nb-2.5Sn-15HA composites were investigated. Potentiodynamic polarization test results indicated that the sintered Ti-35Nb-2.5Sn-15HA composites exhibited higher corrosion resistance with increasing milling time. The corrosion potential and current of the Ti-35Nb-2.5Sn-15HA composite sintered by 12 h milled powders were − 0.261 V and 0.18 μA/cm2, respectively, and this sintered composite showed a stable and wide passivation region. The hemolysis rate of the sintered Ti-35Nb-2.5Sn-15HA composites reduced with increasing milling time and the lowest hemolytic rate of the composites was 0.87\%. In addition, the in vitro cell culture results indicated that the composite sintered by 12 h milled powders had good biocompatibility. These results indicate the significant potential of Ti-35Nb-2.5Sn/xHA composites for biomedical implant applications.",

keywords = "Bioactivity, Electrochemical corrosion, Milling time, Ti-Nb-Sn/HA composites",

author = "Wang Xiaopeng and Kong Fantao and Han Biqing and Chen Yuyong",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Ltd",

year = "2017",

month = nov,

doi = "10.1016/j.jmbbm.2017.07.025",

language = "英语",

volume = "75",

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journal = "Journal of the Mechanical Behavior of Biomedical Materials",

issn = "1751-6161",

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T1 - Electrochemical corrosion and bioactivity of Ti-Nb-Sn-hydroxyapatite composites fabricated by pulse current activated sintering

AU - Xiaopeng, Wang

AU - Fantao, Kong

AU - Biqing, Han

AU - Yuyong, Chen

PY - 2017/11

Y1 - 2017/11

N2 - Ti-Nb-Sn-hydroxyapatite (HA) composites were prepared by mechanical alloying for different times (unmilled, 4, 8 and 12 h), followed by pulse current activated sintering. The effects of the milling time on the electrochemical corrosion resistance and bioactivity of the sintered Ti-35Nb-2.5Sn-15HA composites were investigated. Potentiodynamic polarization test results indicated that the sintered Ti-35Nb-2.5Sn-15HA composites exhibited higher corrosion resistance with increasing milling time. The corrosion potential and current of the Ti-35Nb-2.5Sn-15HA composite sintered by 12 h milled powders were − 0.261 V and 0.18 μA/cm2, respectively, and this sintered composite showed a stable and wide passivation region. The hemolysis rate of the sintered Ti-35Nb-2.5Sn-15HA composites reduced with increasing milling time and the lowest hemolytic rate of the composites was 0.87%. In addition, the in vitro cell culture results indicated that the composite sintered by 12 h milled powders had good biocompatibility. These results indicate the significant potential of Ti-35Nb-2.5Sn/xHA composites for biomedical implant applications.

AB - Ti-Nb-Sn-hydroxyapatite (HA) composites were prepared by mechanical alloying for different times (unmilled, 4, 8 and 12 h), followed by pulse current activated sintering. The effects of the milling time on the electrochemical corrosion resistance and bioactivity of the sintered Ti-35Nb-2.5Sn-15HA composites were investigated. Potentiodynamic polarization test results indicated that the sintered Ti-35Nb-2.5Sn-15HA composites exhibited higher corrosion resistance with increasing milling time. The corrosion potential and current of the Ti-35Nb-2.5Sn-15HA composite sintered by 12 h milled powders were − 0.261 V and 0.18 μA/cm2, respectively, and this sintered composite showed a stable and wide passivation region. The hemolysis rate of the sintered Ti-35Nb-2.5Sn-15HA composites reduced with increasing milling time and the lowest hemolytic rate of the composites was 0.87%. In addition, the in vitro cell culture results indicated that the composite sintered by 12 h milled powders had good biocompatibility. These results indicate the significant potential of Ti-35Nb-2.5Sn/xHA composites for biomedical implant applications.

KW - Bioactivity

KW - Electrochemical corrosion

KW - Milling time

KW - Ti-Nb-Sn/HA composites

UR - https://www.scopus.com/pages/publications/85028949114

U2 - 10.1016/j.jmbbm.2017.07.025

DO - 10.1016/j.jmbbm.2017.07.025

M3 - 文章

C2 - 28756282

AN - SCOPUS:85028949114

SN - 1751-6161

VL - 75

SP - 222

EP - 227

JO - Journal of the Mechanical Behavior of Biomedical Materials

JF - Journal of the Mechanical Behavior of Biomedical Materials

ER -

Electrochemical corrosion and bioactivity of Ti-Nb-Sn-hydroxyapatite composites fabricated by pulse current activated sintering

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Keywords

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