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Efficient Medical Vision-Language Alignment Through Adapting Masked Vision Models

  • Chenyu Lian
  • , Hong Yu Zhou
  • , Dongyun Liang*
  • , Jing Qin
  • , Liansheng Wang*
  • *Corresponding author for this work
  • Xiamen University
  • Hong Kong Polytechnic University
  • Harvard University
  • Fudan University
  • Xiamen Municipal Clinical Research Center for Medical Imaging
  • National Institute for Data Science in Health and Medicine

Research output: Contribution to journalArticlepeer-review

Abstract

Medical vision-language alignment through cross-modal contrastive learning shows promising performance in image-text matching tasks, such as retrieval and zero-shot classification. However, conventional cross-modal contrastive learning (CLIP-based) methods suffer from suboptimal visual representation capabilities, which also limits their effectiveness in vision-language alignment. In contrast, although the models pretrained via multimodal masked modeling struggle with direct cross-modal matching, they excel in visual representation. To address this contradiction, we propose ALTA (ALign Through Adapting), an efficient medical vision-language alignment method that utilizes only about 8% of the trainable parameters and less than 1/5 of the computational consumption required for masked record modeling. ALTA achieves superior performance in vision-language matching tasks like retrieval and zero-shot classification by adapting the pretrained vision model from masked record modeling. Additionally, we integrate temporal-multiview radiograph inputs to enhance the information consistency between radiographs and their corresponding descriptions in reports, further improving the vision-language alignment. Experimental evaluations show that ALTA outperforms the best-performing counterpart by over 4% absolute points in text-to-image accuracy and approximately 6% absolute points in image-to-text retrieval accuracy. The adaptation of vision-language models during efficient alignment also promotes better vision and language understanding.

Original languageEnglish
Pages (from-to)4499-4510
Number of pages12
JournalIEEE Transactions on Medical Imaging
Volume44
Issue number11
DOIs
StatePublished - 2025
Externally publishedYes

Keywords

  • Alignment
  • efficient adaptation
  • multi-modal retrieval
  • radiology
  • vision-language models

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