Effective Identification and Annotation of Fungal Genomes

  • Jian Liu*
  • , Jia Liang Sun
  • , Yong Zhuang Liu
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In the past few decades, the dangers of mycosis have caused widespread concern. With the development of the sequencing technology, the effective analysis of fungal sequencing data has become a hotspot. With the gradual increase of fungal sequencing data, there is now a lack of sufficient approaches for the identification and functional annotation of fungal chromosomal genomes. To overcome this challenge, this paper firstly deals with the approaches of the identification and annotation of fungal genomes based on short and long reads sequenced by using multiple platforms such as Illumina and Pacbio. Then this paper develops an automated bioinformatics pipeline called PFGI for the identification and annotation task. The experimental evaluation on a real-world dataset ENA (European Nucleotide Archive) shows that PFGI provides a user-friendly way to perform fungal identification and annotation based on the sequencing data analysis, and could provide accurate analyzing results, accurate to the species level (97% sequence identity).

Original languageEnglish
Pages (from-to)248-260
Number of pages13
JournalJournal of Computer Science and Technology
Volume36
Issue number2
DOIs
StatePublished - Apr 2021
Externally publishedYes

Keywords

  • bioinformatics pipeline
  • fungal genome
  • fungal identification

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