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Early Screening of Autism in Toddlers via Response-To-Instructions Protocol

  • Jingjing Liu*
  • , Zhiyong Wang
  • , Kai Xu
  • , Bin Ji
  • , Gongyue Zhang
  • , Yi Wang
  • , Jingxin Deng
  • , Qiong Xu
  • , Xiu Xu
  • , Honghai Liu
  • *Corresponding author for this work
  • Shanghai Jiao Tong University
  • University of Portsmouth
  • Children's Hospital of Fudan University
  • Harbin Institute of Technology Shenzhen

Research output: Contribution to journalArticlepeer-review

Abstract

Early screening of autism spectrum disorder (ASD) is crucial since early intervention evidently confirms significant improvement of functional social behavior in toddlers. This article attempts to bootstrap the response-to-instructions (RTIs) protocol with vision-based solutions in order to assist professional clinicians with an automatic autism diagnosis. The correlation between detected objects and toddler's emotional features, such as gaze, is constructed to analyze their autistic symptoms. Twenty toddlers between 16-32 months of age, 15 of whom diagnosed with ASD, participated in this study. The RTI method is validated against human codings, and group differences between ASD and typically developing (TD) toddlers are analyzed. The results suggest that the agreement between clinical diagnosis and the RTI method achieves 95% for all 20 subjects, which indicates vision-based solutions are highly feasible for automatic autistic diagnosis.

Original languageEnglish
Pages (from-to)3914-3924
Number of pages11
JournalIEEE Transactions on Cybernetics
Volume52
Issue number5
DOIs
StatePublished - 1 May 2022
Externally publishedYes

Keywords

  • Autistic early screening
  • gaze estimation
  • social behavior disorder

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