Divergent Synthesis of Marine Natural Products Siphonodictyal B, Corallidictyals C/D, and Liphagal Based on the Early Presence of an Aldehyde Group Instead of a Late-Stage Introduction

Jun Li Wang; Hui Jing Li; Yan Chao Wu

doi:10.1021/acs.joc.8b00989

Divergent Synthesis of Marine Natural Products Siphonodictyal B, Corallidictyals C/D, and Liphagal Based on the Early Presence of an Aldehyde Group Instead of a Late-Stage Introduction

Jun Li Wang
, Hui Jing Li
, Yan Chao Wu^*

^*Corresponding author for this work

School of Marine Science and Technology, Harbin Institute of Technology Weihai
Peking University

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

An iodine-promoted sunlight-induced olefin Z/E isomerization reaction together with a palladium-catalyzed direct cross-coupling reaction of a drimanal hydrazone and an iodobenzaldehyde, without touching the aromatic aldehyde group, facilitated a divergent and expeditious access to bioactive marine natural products siphonodictyal B, corallidictyals C/D, and liphagal based on the early presence of an aldehyde group instead of a late-stage introduction.

Original language	English
Pages (from-to)	8716-8723
Number of pages	8
Journal	Journal of Organic Chemistry
Volume	83
Issue number	15
DOIs	https://doi.org/10.1021/acs.joc.8b00989
State	Published - 3 Aug 2018
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 14 Life Below Water

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10.1021/acs.joc.8b00989

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title = "Divergent Synthesis of Marine Natural Products Siphonodictyal B, Corallidictyals C/D, and Liphagal Based on the Early Presence of an Aldehyde Group Instead of a Late-Stage Introduction",

abstract = "An iodine-promoted sunlight-induced olefin Z/E isomerization reaction together with a palladium-catalyzed direct cross-coupling reaction of a drimanal hydrazone and an iodobenzaldehyde, without touching the aromatic aldehyde group, facilitated a divergent and expeditious access to bioactive marine natural products siphonodictyal B, corallidictyals C/D, and liphagal based on the early presence of an aldehyde group instead of a late-stage introduction.",

author = "Wang, \{Jun Li\} and Li, \{Hui Jing\} and Wu, \{Yan Chao\}",

note = "Publisher Copyright: {\textcopyright} 2018 American Chemical Society.",

year = "2018",

month = aug,

day = "3",

doi = "10.1021/acs.joc.8b00989",

language = "英语",

volume = "83",

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journal = "Journal of Organic Chemistry",

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}

Divergent Synthesis of Marine Natural Products Siphonodictyal B, Corallidictyals C/D, and Liphagal Based on the Early Presence of an Aldehyde Group Instead of a Late-Stage Introduction. / Wang, Jun Li; Li, Hui Jing ; Wu, Yan Chao.
In: Journal of Organic Chemistry, Vol. 83, No. 15, 03.08.2018, p. 8716-8723.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Divergent Synthesis of Marine Natural Products Siphonodictyal B, Corallidictyals C/D, and Liphagal Based on the Early Presence of an Aldehyde Group Instead of a Late-Stage Introduction

AU - Wang, Jun Li

AU - Li, Hui Jing

AU - Wu, Yan Chao

PY - 2018/8/3

Y1 - 2018/8/3

N2 - An iodine-promoted sunlight-induced olefin Z/E isomerization reaction together with a palladium-catalyzed direct cross-coupling reaction of a drimanal hydrazone and an iodobenzaldehyde, without touching the aromatic aldehyde group, facilitated a divergent and expeditious access to bioactive marine natural products siphonodictyal B, corallidictyals C/D, and liphagal based on the early presence of an aldehyde group instead of a late-stage introduction.

AB - An iodine-promoted sunlight-induced olefin Z/E isomerization reaction together with a palladium-catalyzed direct cross-coupling reaction of a drimanal hydrazone and an iodobenzaldehyde, without touching the aromatic aldehyde group, facilitated a divergent and expeditious access to bioactive marine natural products siphonodictyal B, corallidictyals C/D, and liphagal based on the early presence of an aldehyde group instead of a late-stage introduction.

UR - https://www.scopus.com/pages/publications/85048112161

U2 - 10.1021/acs.joc.8b00989

DO - 10.1021/acs.joc.8b00989

M3 - 文章

C2 - 29869493

AN - SCOPUS:85048112161

SN - 0022-3263

VL - 83

SP - 8716

EP - 8723

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 15

ER -

Divergent Synthesis of Marine Natural Products Siphonodictyal B, Corallidictyals C/D, and Liphagal Based on the Early Presence of an Aldehyde Group Instead of a Late-Stage Introduction

Abstract

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