Development of high flux immunoassay analyzer based on chemiluminescence

According to the requirements of high sensitivity and high flux of clinical immunoassay system, an immunoassay analyzer is developed based on the principle of chemiluminescence. The system prototype is designed by considering the chemiluminescence immunoassay steps and applying the idea of modular design and pipeline operation. Based on the analysis and simulation of milliliter level liquid filling-up process, the optimized requirements of relative sampling parameter is given. The design requirement for the magnetic field is then presented based on the analysis of separating immunocomplex process. The design of the pipeline modular and control system is completed according to the programmed manipulation and detection speed. Finally, the full-functional equipment is tested and the detection results show that the developed analyzer has high detection accuracy and good compatibility and it can fully meet the relevant specific standard of National Ministry of Health. In addition, implementation of stability tests ensures that at least 180 samples can be processed within one hour. The developed analyzer has been successfully applied in several hospitals.