Development and evaluation of ultramicro electrode ensembles based on 1.6-hexanedithiol self-assembled modified layer and its application for HRP detection

Lixin Cao; Qingchuan Li; Jiesheng Ji; Peisheng Yan; Tao Wang

Development and evaluation of ultramicro electrode ensembles based on 1.6-hexanedithiol self-assembled modified layer and its application for HRP detection

Lixin Cao^*
, Qingchuan Li
, Jiesheng Ji
, Peisheng Yan
, Tao Wang

^*Corresponding author for this work

School of Ocean Engineering, Harbin Institute of Technology Weihai

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The 1.6-hexanedithiol (HDT) chemically modified gold (HDT/Au) electrode were prepared by self-assembly. The HDT modified layer blocked the heterogeneous electrolysis of [Fe (CN)6]3-/4- strongly except sites of pinholes and defects which behaved like ultramicro electrode ensembles (UMEs). The features of UMEs and the electrochemcial characteristics of [Fe(CN)6]3-/4 at UMEs with different modifying hours were studied by electrochemical impedance spectroscopy. HDT modified gold electrode promoted the electrochemical process for redox reaction of 2,3-diaminophenazine (DAP), the product of OPD-H₂O₂-HRP enzymatic catalyst reaction system and blocked hydrogen evolution effectively. The detection limit determined by square wave was 10-11g/ml, which is about one order of magnitude lower than the reported lowest results.

Original language	English
Pages (from-to)	3074-3083
Number of pages	10
Journal	International Journal of Electrochemical Science
Volume	8
Issue number	3
State	Published - Mar 2013
Externally published	Yes

Keywords

1.6-hexanedithiol
Horseradish peroxide
Self-assembling modification
Ultramicro electrode ensembles

Cite this

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title = "Development and evaluation of ultramicro electrode ensembles based on 1.6-hexanedithiol self-assembled modified layer and its application for HRP detection",

abstract = "The 1.6-hexanedithiol (HDT) chemically modified gold (HDT/Au) electrode were prepared by self-assembly. The HDT modified layer blocked the heterogeneous electrolysis of [Fe (CN)6]3-/4- strongly except sites of pinholes and defects which behaved like ultramicro electrode ensembles (UMEs). The features of UMEs and the electrochemcial characteristics of [Fe(CN)6]3-/4 at UMEs with different modifying hours were studied by electrochemical impedance spectroscopy. HDT modified gold electrode promoted the electrochemical process for redox reaction of 2,3-diaminophenazine (DAP), the product of OPD-H2O2-HRP enzymatic catalyst reaction system and blocked hydrogen evolution effectively. The detection limit determined by square wave was 10-11g/ml, which is about one order of magnitude lower than the reported lowest results.",

keywords = "1.6-hexanedithiol, Horseradish peroxide, Self-assembling modification, Ultramicro electrode ensembles",

author = "Lixin Cao and Qingchuan Li and Jiesheng Ji and Peisheng Yan and Tao Wang",

year = "2013",

month = mar,

language = "英语",

volume = "8",

pages = "3074--3083",

journal = "International Journal of Electrochemical Science",

issn = "1452-3981",

publisher = "Elsevier B.V.",

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}

TY - JOUR

T1 - Development and evaluation of ultramicro electrode ensembles based on 1.6-hexanedithiol self-assembled modified layer and its application for HRP detection

AU - Cao, Lixin

AU - Li, Qingchuan

AU - Ji, Jiesheng

AU - Yan, Peisheng

AU - Wang, Tao

PY - 2013/3

Y1 - 2013/3

N2 - The 1.6-hexanedithiol (HDT) chemically modified gold (HDT/Au) electrode were prepared by self-assembly. The HDT modified layer blocked the heterogeneous electrolysis of [Fe (CN)6]3-/4- strongly except sites of pinholes and defects which behaved like ultramicro electrode ensembles (UMEs). The features of UMEs and the electrochemcial characteristics of [Fe(CN)6]3-/4 at UMEs with different modifying hours were studied by electrochemical impedance spectroscopy. HDT modified gold electrode promoted the electrochemical process for redox reaction of 2,3-diaminophenazine (DAP), the product of OPD-H2O2-HRP enzymatic catalyst reaction system and blocked hydrogen evolution effectively. The detection limit determined by square wave was 10-11g/ml, which is about one order of magnitude lower than the reported lowest results.

AB - The 1.6-hexanedithiol (HDT) chemically modified gold (HDT/Au) electrode were prepared by self-assembly. The HDT modified layer blocked the heterogeneous electrolysis of [Fe (CN)6]3-/4- strongly except sites of pinholes and defects which behaved like ultramicro electrode ensembles (UMEs). The features of UMEs and the electrochemcial characteristics of [Fe(CN)6]3-/4 at UMEs with different modifying hours were studied by electrochemical impedance spectroscopy. HDT modified gold electrode promoted the electrochemical process for redox reaction of 2,3-diaminophenazine (DAP), the product of OPD-H2O2-HRP enzymatic catalyst reaction system and blocked hydrogen evolution effectively. The detection limit determined by square wave was 10-11g/ml, which is about one order of magnitude lower than the reported lowest results.

KW - 1.6-hexanedithiol

KW - Horseradish peroxide

KW - Self-assembling modification

KW - Ultramicro electrode ensembles

UR - https://www.scopus.com/pages/publications/84875064344

M3 - 文章

AN - SCOPUS:84875064344

SN - 1452-3981

VL - 8

SP - 3074

EP - 3083

JO - International Journal of Electrochemical Science

JF - International Journal of Electrochemical Science

IS - 3

ER -

Development and evaluation of ultramicro electrode ensembles based on 1.6-hexanedithiol self-assembled modified layer and its application for HRP detection

Abstract

Keywords

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