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Design of detection electrode on contactless conductivity detection in capillary electrophoresis microchip

  • Harbin Institute of Technology

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Contactless conductivity detection has attained great attention in the last decade in capillary electrophoresis. But contactless conductivity detection is restricted by its sensitivity, how to improve detection sensitivity has become the key of contactless conductivity. In this paper a novel extended model for the detection cell consisting of a network of resistors and capacitors is proposed according to the structure of contactless conductivity detection. The effect of the detector geometry on the sensitivity of contactless conductivity is studied. By simulation, the optimal parameters are obtained. Sandwich electrode structure was established to improve the performance of the detector and minimize the stray capacitance between the electrodes. Using the optimal electrode structure, the two peaks corresponding to K+ and Mg 2+ are clearly resolved with complete separation.

Original languageEnglish
Title of host publication8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013
Pages1104-1107
Number of pages4
DOIs
StatePublished - 2013
Event8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013 - Suzhou, China
Duration: 7 Apr 201310 Apr 2013

Publication series

Name8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013

Conference

Conference8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013
Country/TerritoryChina
CitySuzhou
Period7/04/1310/04/13

Keywords

  • Capillary electrophoresis
  • capacitance
  • contactless conductivity detection
  • detection electrode

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