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Design and synthesis of novel fluorine-containing acrylates

  • Yan Chao Wu*
  • , Chao Wu
  • , Xiao Mao Zou
  • , Fang Zhong Hu
  • , Hua Zheng Yang
  • *Corresponding author for this work
  • Nankai University

Research output: Contribution to journalArticlepeer-review

Abstract

A series of novel fluorine-containing acrylates 6a-6g were synthesized via the condensation of ethyl cyanoacetate and trifluoroacetic anhydride, followed by chloridization and the coupling reaction with amines. These new compounds exhibited some biological activity as preliminary bioassay indicated. A plausible reaction mechanism was outlined and discussed.

Original languageEnglish
Pages (from-to)1293-1296
Number of pages4
JournalChinese Chemical Letters
Volume16
Issue number10
StatePublished - Oct 2005
Externally publishedYes

Keywords

  • Acrylates
  • Fluorine-containing compound
  • Synthesis

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