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Design and Development of PHBV/PLA Artificial Blood Vessels

  • Xueyan Ouyang
  • , Yanxue Ma*
  • , Guangchang Zhu
  • , Qiong Wu
  • , Yuling Li
  • *Corresponding author for this work
  • Donghua University
  • Beijing Normal University
  • Tsinghua University

Research output: Contribution to journalArticlepeer-review

Abstract

In the research, a β-hydroxybutyrate and β-hydroxyvalerate copolymer (PHBV)/polylactic acid (PLA) artificial blood vessel was designed and developed, and it was also implanted in vivo for a period of time to observe its biocompatibility and degradation performance. The results showed that the developed PHBV/PLA artificial blood vessel could be used to replace the natural blood vessel, but its degradation rate was too fast and the mechanical supporting force was insufficient. Thus, properties of the PHBV/PLA need to be further improved.

Original languageEnglish
Pages (from-to)212-215
Number of pages4
JournalJournal of Donghua University (English Edition)
Volume34
Issue number2
StatePublished - 30 Apr 2017
Externally publishedYes

Keywords

  • Artificial blood vessels
  • Bio-compatibility
  • Degradation rate
  • Supporting force
  • Woven
  • β-hydroxybutyrate and β-hydroxyvalerate copolymer (PHBV)/polylactic acid (PLA)

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