Curvature-based correction algorithm for automatic lung segmentation on chest CT images

In order to ameliorate the lung defects caused by missed juxtapleural nodules in lung segmentation on chest computed tomography (CT) images, we develop a Newton-Cotes-based smoothing algorithm (NCBS) which is used as a preliminary step to remove noises as many as possible. Next considering the crescent outline features of the lung, we propose a curvature-based correction algorithm (CBC) for the determination of the correction threshold. The application of the proposed algorithms is demonstrated in the process of lung segmentation and the experimental results on 25 real datasets are illustrated. Furthermore, some experiments are conducted to investigate the effects of the key parameters in CBC on the performances of lung segmentation so as to decide their optimal values. In addition, the CBC is compared with other methods analytically and experimentally. The overall results show that our proposed algorithm in lung segmentation excels the related methods on the capability of automatic selection of the correction threshold, as well as the performances of accuracy, efficiency and feasibility.