Crosslinking catalysis-active center of hemin on the protein scaffold toward peroxidase mimic with powerful catalysis

Minmin Dong; Liyan Zhang; Ru Li; Rui Li; Shuying Li; Yao Jiang; Yuchun Qiao; Zhiqiang Duan; Quanfu Wang; Hua Wang

doi:10.1039/c6ra07139b

Crosslinking catalysis-active center of hemin on the protein scaffold toward peroxidase mimic with powerful catalysis

Minmin Dong
, Liyan Zhang
, Ru Li
, Rui Li
, Shuying Li
, Yao Jiang
, Yuchun Qiao
, Zhiqiang Duan
, Quanfu Wang
, Hua Wang^*

^*Corresponding author for this work

Qufu Normal University
School of Marine Science and Technology, Harbin Institute of Technology Weihai

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

An enzyme mimic synthesis protocol has been proposed by simply cross-linking the redox active center of peroxidase onto a protein scaffold. Colorimetric assays and kinetic studies indicate that the developed peroxidase mimic can present much stronger catalysis and better aqueous stability than native hemin.

Original language	English
Pages (from-to)	47595-47599
Number of pages	5
Journal	RSC Advances
Volume	6
Issue number	53
DOIs	https://doi.org/10.1039/c6ra07139b
State	Published - 2016
Externally published	Yes

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@article{82847694057e40948f727fc62c99cdc3,

title = "Crosslinking catalysis-active center of hemin on the protein scaffold toward peroxidase mimic with powerful catalysis",

abstract = "An enzyme mimic synthesis protocol has been proposed by simply cross-linking the redox active center of peroxidase onto a protein scaffold. Colorimetric assays and kinetic studies indicate that the developed peroxidase mimic can present much stronger catalysis and better aqueous stability than native hemin.",

author = "Minmin Dong and Liyan Zhang and Ru Li and Rui Li and Shuying Li and Yao Jiang and Yuchun Qiao and Zhiqiang Duan and Quanfu Wang and Hua Wang",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2016.",

year = "2016",

doi = "10.1039/c6ra07139b",

language = "英语",

volume = "6",

pages = "47595--47599",

journal = "RSC Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Crosslinking catalysis-active center of hemin on the protein scaffold toward peroxidase mimic with powerful catalysis

AU - Dong, Minmin

AU - Zhang, Liyan

AU - Li, Ru

AU - Li, Rui

AU - Li, Shuying

AU - Jiang, Yao

AU - Qiao, Yuchun

AU - Duan, Zhiqiang

AU - Wang, Quanfu

AU - Wang, Hua

PY - 2016

Y1 - 2016

N2 - An enzyme mimic synthesis protocol has been proposed by simply cross-linking the redox active center of peroxidase onto a protein scaffold. Colorimetric assays and kinetic studies indicate that the developed peroxidase mimic can present much stronger catalysis and better aqueous stability than native hemin.

AB - An enzyme mimic synthesis protocol has been proposed by simply cross-linking the redox active center of peroxidase onto a protein scaffold. Colorimetric assays and kinetic studies indicate that the developed peroxidase mimic can present much stronger catalysis and better aqueous stability than native hemin.

UR - https://www.scopus.com/pages/publications/84971343419

U2 - 10.1039/c6ra07139b

DO - 10.1039/c6ra07139b

M3 - 文章

AN - SCOPUS:84971343419

SN - 2046-2069

VL - 6

SP - 47595

EP - 47599

JO - RSC Advances

JF - RSC Advances

IS - 53

ER -

Crosslinking catalysis-active center of hemin on the protein scaffold toward peroxidase mimic with powerful catalysis

Abstract

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