Conjugation of porphyrin to nanohybrid cerasomes for photodynamic diagnosis and therapy of cancer

Xiaolong Liang; Xiaoda Li; Xiuli Yue; Zhifei Dai

doi:10.1002/anie.201103557

Conjugation of porphyrin to nanohybrid cerasomes for photodynamic diagnosis and therapy of cancer

Xiaolong Liang
, Xiaoda Li
, Xiuli Yue
, Zhifei Dai^*

^*Corresponding author for this work

School of Environment

Harbin Institute of Technology

Research output: Contribution to journal › Article › peer-review

162 Scopus citations

Abstract

Shining light on cancer cells: A cerasomal photosensitizer of high stability and loading efficiency was developed by conjugation of a porphyrin molecule to an organoalkoxysilylated lipid followed by sol-gel and self-assembly processes (see picture). This nanoformulation showed intrinsic fluorescence and significant damage to tumor cells under photoirradiation.

Original language	English
Pages (from-to)	11622-11627
Number of pages	6
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	49
DOIs	https://doi.org/10.1002/anie.201103557
State	Published - 2 Dec 2011

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

cancer
liposomes
photodynamic therapy
self-assembly
sol-gel processes

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10.1002/anie.201103557

Cite this

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abstract = "Shining light on cancer cells: A cerasomal photosensitizer of high stability and loading efficiency was developed by conjugation of a porphyrin molecule to an organoalkoxysilylated lipid followed by sol-gel and self-assembly processes (see picture). This nanoformulation showed intrinsic fluorescence and significant damage to tumor cells under photoirradiation.",

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T1 - Conjugation of porphyrin to nanohybrid cerasomes for photodynamic diagnosis and therapy of cancer

AU - Liang, Xiaolong

AU - Li, Xiaoda

AU - Yue, Xiuli

AU - Dai, Zhifei

PY - 2011/12/2

Y1 - 2011/12/2

N2 - Shining light on cancer cells: A cerasomal photosensitizer of high stability and loading efficiency was developed by conjugation of a porphyrin molecule to an organoalkoxysilylated lipid followed by sol-gel and self-assembly processes (see picture). This nanoformulation showed intrinsic fluorescence and significant damage to tumor cells under photoirradiation.

AB - Shining light on cancer cells: A cerasomal photosensitizer of high stability and loading efficiency was developed by conjugation of a porphyrin molecule to an organoalkoxysilylated lipid followed by sol-gel and self-assembly processes (see picture). This nanoformulation showed intrinsic fluorescence and significant damage to tumor cells under photoirradiation.

KW - cancer

KW - liposomes

KW - photodynamic therapy

KW - self-assembly

KW - sol-gel processes

UR - https://www.scopus.com/pages/publications/82455219365

U2 - 10.1002/anie.201103557

DO - 10.1002/anie.201103557

M3 - 文章

C2 - 22002770

AN - SCOPUS:82455219365

SN - 1433-7851

VL - 50

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 49

ER -

Conjugation of porphyrin to nanohybrid cerasomes for photodynamic diagnosis and therapy of cancer

Abstract

UN SDGs

Keywords

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