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Class IIa bacteriocins: Diversity and new developments

  • Yanhua Cui
  • , Chao Zhang
  • , Yunfeng Wang*
  • , John Shi
  • , Lanwei Zhang
  • , Zhongqing Ding
  • , Xiaojun Qu
  • , Hongyu Cui
  • *Corresponding author for this work
  • Harbin Institute of Technology
  • Chinese Academy of Agricultural Sciences
  • Agriculture and Agri-Food Canada
  • Heilongjiang Academy of Sciences

Research output: Contribution to journalReview articlepeer-review

Abstract

Class IIa bacteriocins are heat-stable, unmodified peptides with a conserved amino acids sequence YGNGV on their N-terminal domains, and have received much attention due to their generally recognized as safe (GRAS) status, their high biological activity, and their excellent heat stability. They are promising and attractive agents that could function as biopreservatives in the food industry. This review summarizes the new developments in the area of class IIa bacteriocins and aims to provide uptodate information that can be used in designing future research.

Original languageEnglish
Pages (from-to)16668-16707
Number of pages40
JournalInternational Journal of Molecular Sciences
Volume13
Issue number12
DOIs
StatePublished - Dec 2012

Keywords

  • Class IIa bacteriocin
  • Discovery
  • Diversity
  • Genetic organization
  • Lactic acid bacteria

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