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Chemiluminescence determination of terbutaline sulfate in bovine urine and pharmaceutical preparations based on enhancement of the 2-phenyl-4, 5-di (2-furyl) imidazole-potassium ferricyanide system

  • Lu Han
  • , Yumin Zhang*
  • , Jing Kang
  • , Jieli Tang
  • , Yihua Zhang*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In this paper, a novel chemiluminescence (CL) system, 2-phenyl-4, 5-di (2-furyl) imidazole (PDFI)-potassium ferricyanide, for the determination of terbutaline sulfate was described. The method was based on enhancement of CL emission of PDFI-potassium ferricyanide system in the presence of terbutaline sulfate. Under the optimum conditions, the enhanced chemiluminescence intensity is linearly related to the concentration of terbutaline sulfate. The proposed method has been successfully applied to the determination of terbutaline sulfate in bovine urine and pharmaceutical preparations with satisfactory results. Furthermore, the possible mechanism of chemiluminescence reaction was also discussed briefly.

Original languageEnglish
Pages (from-to)141-145
Number of pages5
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume58
Issue number1
DOIs
StatePublished - 25 Jan 2012
Externally publishedYes

Keywords

  • 2-Phenyl-4, 5-di (2-furyl) imidazole
  • Chemiluminescence
  • Potassium ferricyanide
  • Terbutaline sulfate

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