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An Ultra-Fast and Large-Scale Fabrication Method for Paper-Based Microfluidic Chips

  • Fuzhou University
  • Fujian Provincial Hospital

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Portable electronic devices and wireless communication enable a broad range of applications including environmental surveillance, food safety monitoring and point-of-care testing. Particularly, by incorporating smartphone and microfluidic paper-based device, rapid analysis, mobile laboratories for chemical assay, remote sensing and data management become more available. In this work, we designed and fabricated a 12-unit paper chip for colorimetric detection of metals. 48 chips can be obtained on a single A4 size paper within 5, min. Additive manufacturing technology was employed to construct the experimental platform. A cellphone’s camera was used to capture colorimetric images, and then the RGB values of the color images were converted to grayscale via a self-built App. The intensity reflecting metal concentrations were processed and analyzed by the same app and a remote server. To demonstrate the utility of this approach, Fe solutions were tested. The detection limit of this method is 0.2, μg. The presented device and data processing tools hold a potential to assist mobile sensing, pollution detection and healthcare in routine work.

Original languageEnglish
Title of host publicationAdvances in Mechanical Design - Proceedings of the 2017 International Conference on Mechanical Design, ICMD 2017
EditorsChangle Xiang, Jianrong Tan, Feng Gao
PublisherSpringer Netherlands
Pages1561-1572
Number of pages12
ISBN (Print)9789811065521
DOIs
StatePublished - 2018
Externally publishedYes
EventInternational Conference on Mechanical Design, ICMD 2017 - Beijing, China
Duration: 13 Oct 201715 Oct 2017

Publication series

NameMechanisms and Machine Science
Volume55
ISSN (Print)2211-0984
ISSN (Electronic)2211-0992

Conference

ConferenceInternational Conference on Mechanical Design, ICMD 2017
Country/TerritoryChina
CityBeijing
Period13/10/1715/10/17

Keywords

  • Image processing by smartphone
  • Metal detection
  • Paper-based microfluidics

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